The Pap Smear, Cervical Dysplasia and Cancer Flashcards
1
Q
Two types of epithelium in the cervix
A
Columnar and stratified nonkeratinizing squamous epithelia
2
Q
Significance of Squamocolumnar junction (SCJ)
A
site where greater than 90% of cervical neoplasia arise
3
Q
Cervical cancer and CIN are caused by…
A
HPV
4
Q
Important HPV types that cause cancer
A
16, 18, 31, 45
5
Q
Risk factors for cervical neoplasia
A
-More than one sexual partner or a male sexual partner who has had
sex with more than one person
-Male sexual partner who has had a sexual partner with cervical cancer
-Smoking
-HIV
-Organ transplant
-Sexually transmitted infections
-Diethylstilbestrol exposure
-History of cervical cancer or high grade lesion
-Infrequent or absent pap screening tests
