The Oxygen Dissociation Curve Flashcards
the oxygen dissociation curve shows the rate at which
oxygen associates, and also dissociates, with haemoglobin at different partial pressures of oxygen (pO2)
Partial pressure of oxygen refers to the
pressure exerted by oxygen within a mixture of gases; it is a measure of oxygen concentration
Haemoglobin is referred to as being saturated when
all of its oxygen binding sites are taken up with oxygen; so when it contains four oxygen molecules
affinity for oxygen is
The ease with which haemoglobin binds and dissociates with oxygen
When haemoglobin has a high affinity it
binds easily and dissociates slowly
When haemoglobin has a low affinity for oxygen it
binds slowly and dissociates easily
In other liquids, such as water, we would expect oxygen to becomes associated with water, or to dissolve, at a constant rate, providing a straight line on a graph, but with haemoglobin oxygen binds at different rates as the pO2 changes; hence the resulting curve
It can be said that haemoglobin’s affinity for oxygen changes at different
partial pressures of oxygen