Digestion of Proteins by Proteases Flashcards
Protein digestion begins in the
Protein digestion begins in the lumen of the stomach by protease enzymes
A protease enzyme called an endopeptidase hydrolyses
peptide bonds in the middle of polymer proteins chain creating smaller sized protein “chunks”
endopeptidase This enzyme is secreted along with
hydrochloric acid, meaning the pH in the stomach is low and therefore acidic
The partially digested food moves from the stomach into the
small intestine
Fluid secreted by the pancreas travels to the small intestine and helps to
neutralize the acidic mixture and increase the pH.
This pancreatic juice contains
endopeptidases and exopeptidases
Exopeptidases hydrolyse
hydrolyse peptide bonds at the ends of polypeptide chains to produce dipeptides
Lastly, there are dipeptidase enzymes found within the
ileum and duodenum
These enzymes dipeptidase hydrolyse dipeptides into
amino acids which can be transported from to epithelial and then bloodstream
Where does digestion of proteins happen
First stomach then duodenum and ileum