The Nervous System Flashcards
What are neurones
Specialised cells for the rapid transmission of nerve impulses
What are nerves
Bundles of nerve fibres called axons or dendrons which are long extensions of a single neurone
Differences between sensory and motor neurones: dendron
Sensory neuron has a long dendron and motor no one has no dendron
Differences between sensory and motor neurones: axon
Sensory have a short axons and motor has a long axon
Differences between sensory and motor neurones: cell body
Sensory cell body attached to dendron motor cell body at end of neurone
Differences between sensory and motor neurones: dendrites
Motor dendrites connect to cell body
Cell body
Contains nucleus and other organelles surrounded by granular cytoplasm
Dendrites
Highly branched fibres that receive stimuli from receptors or adjacent neurones they connect impulses towards the cell body
Axon
Extension of the neurone carries nerve impulses away from the cell body transmits nerve impulses to other neurons or receptors
Myelin sheath
Thick insulating layer around axon that has high electrical resistance from Schwann cells helps transmit neurons faster
Node of ranvier
Gaps along the myelin sheath where axon is exposed which aids the transmission of the nerve action potential along the axon
What is the resting potential
-70mv
Describe resting potential
The sodium potassium pump creates a concentration gradient across the membrane
K+ diffuses out down the concentration gradient so the outside is positive and the inside is negative
The electrical gradient will put potassium back into the cell
At -70mv potential difference the two gradients counteract eachother- no movement of k
What is resting potential maintained by
Sodium pump, relative permeability of membrane, and movement of potassium ions
What is action potential?
Change in permeability if cell membrane to sodium ions which causes a temporary reversal of charge
Describe an action potential
Few sodium ions diffuse in from Axon
Sodium gates open and sodium floods in down the concentration of electrochemical gradient
Axon positive on the inside and negative on the outside for 1 ms
Depolarisation= +40mv
At the end of this brief depolarisation sodium channels close again and Excess sodium rapidly pumped out actively in preparation for the next impulse
Describe the 4 stages of ionic changes during axon excitation
1) Voltage dependent sodium channels open so they flow into the axon depolarising the membrane
2) Voltages dependent sodium channels close and the volted potassium channels open- potassium leaves axon depolarising membrane
Sodium is pumped out
3) Hyperpolarisation slight overshoot of the membrane potential to more negative than resting potential
4) Voltage dependent potassium channels close potassium diffuses back into the axon to recreate resting potential
Salatory conduction
In myelinated neurones ions can only pass in and out of the axons freely at the nodes of Ranvier- action potentials only occur at the nodes. Action potential jumps from one to the next which speeds up transmission as ionic movements associated with action potential occur less frequently and less time
How does the action potential move across the synapse
Calcium channels open in the presynaptic neuron
Calcium ions flood in due to reversal of charges
Vesicles on the pre-synaptic neurone fuse with the membrane
Neurotransmitter ACh is released into the synaptic cleft by exocytosis
It diffuses across the synaptic cleft and binds to receptors on sodium ion channels on post synaptic neurone
Channels open and sodium ions flood in down the concentration gradient setting an action potential
Postsynaptic membrane depolarises if the threshold value is reached an action potential is generated
ACh is broken Down into acetyl and co-line in the synaptic left which defuses back into the presynaptic neuron ATP is used to re-combine them
Role of synapses: convergence
Many pre-synaptic neurone is converge on any single postsynaptic neuron
Many stimuli warning us about one danger
Role of synapses: divergence
Axons of most pre-synaptic neurons divided into many branches that diverge to many postsynaptic neurones
Role of synapses: acclimatisation
After repeated stimulation a synapse run out of vesicles so no response
Neurotransmitters: cholinergic nerves
Nerves using acetylcholine in voluntary response
Neurotransmitters: Adrenergic nerves
Use noradrenaline in the autonomic system
Autonomic system: sympathetic
Secretes noradrenaline
Increased heart rate, pupil dilation and ventilation
Autonomic system: parasympathetic
Secretes acetylcholine
Decreased heart rate, pupil construction, decreased ventilation
The reflex arc
Nerves are sent to the spinal-cord not the brain for a faster reaction
Structure of the spinal-cord
Tube made up of core grey matter surrounded by white matter
Grey matter
Consists of the cell bodies of neurons in the CNS
White matter
Nerve fibres of neurons in the CNS