The Musculoskeletal System Flashcards
What is skeletal muscle?
responsible for voluntary movement and innervated by the somatic nervous system
What are sarcomeres?
the functional contractile unit of striated muscle; repeating units of actin and myosin; thick and thin filaments
What are slow-twitch fibers?
aka “red fibers”; have high myoglobin content and primarily derive their energy aerobically
What is myoglobin?
an oxygen carrier that uses iron in a heme group to bind oxygen, imparting a red color
What is fast-twitch fibers?
aka “white fibers”; contain much less myoglobin
Muscles that contract rapidly but fatigue quickly, contain mostly _____ fibers?
white
Muscles that contract slowly but can sustain activity contain mostly ______ fibers?
red
What is smooth muscle?
responsible for involuntary action and innervated by autonomic nervous system
Which types of muscle are multinucleated?
skeletal, cardiac (sometimes)
What is tonus?
a constant state of low-level contraction, as may be seen in blood vessels; more sustained contractions
What is myogenic activity?
smooth muscle can actually contract without nervous system input and responses directly to stretch or other stimuli
What is cardiac muscle?
contraction is involuntary and innervated by the autonomic nervous system; looks striated; also exhibits myogenic activity
What are intercalated discs?
connect cardiac cells and contain gap junctions
What are gap junctions?
connections between the cytoplasm of adjacent cells allowing for the flow of ions directly between the cells
What are thick filaments?
organized bundles of myosin
What are thin filaments?
made of actin, troponin and tropomyosin
What is titin?
a protein that acts as a spring and anchors the actin and myosin filaments together; preventing excessive stretching of the muscle
What are myofibrils?
sarcomeres attached end to end
What is the sarcoplasmic reticulum (SR)?
a modified endoplasmic reticulum that contains a high concentration of Ca2+ ions and covers myofibrils
What is the sarcoplasm?
modified cytoplasm located just outside the SR
What is the sarcolemma?
the cell membrane of a myocyte; capable of propagating an action potential and can distribute the action potential to all sarcomeres in the muscle
What are transverse tubules (T-tubules)?
tubules that are oriented perpendicular to the myofibrils through which the action potentials can be transmitted
What is another word for a muscle cell?
myocyte
What is a muscle fiber?
a bunch of myofibrils arrange in parallel; aka a myocyte
Pathway of the muscle contration
Neuromuscular junction —> motor neurons —> nerve terminal —> acetylcholine to receptors —> depolarization
What is the neuromuscular junction?
where the nervous system communicates with muscles via motor neurons
What is the motor end plate?
nerve terminal or synaptic bouton
What is a motor unit?
the nerve terminal and its myocytes