The Male Reproductive System Flashcards

1
Q

Which parts of the male reproductive tract produce elements of seminal fluid?

A

Seminal Vesicle
Prostate Gland

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2
Q

Transport of gametes starts in the…

A

testes

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3
Q

All seminiferous tubules drain into the…

A

mediastinum

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4
Q

Mediastinum

A

Dense CT with blood vessels
Contains rete testis

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5
Q

Where do gametes go after the rete testis?

A

Into the Efferent ductules

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6
Q

What epithelium is found in the Efferent ductules?

Efferent Ductules = Ductuli Efferentes

A

Pseudostratified columnar epithelium
Interspered with tall and short columnar cells

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7
Q

What is the difference between the short and tall columnar cells in the efferent ductues?

A

Short: microvilli - reabsorb fluid secreted in the seminiferous tubules
Tall: Cilia - move spermatids

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8
Q

Efferent Ductules Histology

A

Pseudostratified epithelium
Short and Tall columnar cells
Irregular appearance of lumen
CT between

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9
Q

From the Efferent Ductles, spermatids enter the…

A

Epididymis

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10
Q

What is the function of the epididymis?

A

Gamete maturation and storage

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11
Q

How are mature sperm modified in the epididymis?

A

Nuclear DNA condenses
Additional loss of cytoplasm
Alterations to acrosomal membrane (anterior pole)
Motility

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12
Q

What causes motility of spermatids?

A

Altered phosphatase activity regulated by cAMP, Ca2+, and intracellular pH

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13
Q

What epithelium is found in the epididymis?

A

Pseudostratified columnar epithelium with stereocilia

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14
Q

The Epididymis histologically

Epididymis = Ductus Epididymis

A

Lumen appears regular and smooth
Pseudostratified columnar epithelium with stereocilia

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15
Q

What is the function of stereocilia in the epididymis?

A

Detect lumen contents
Regulates secretion and absorption by principal cells in order to make the right environment for maturation and storage of sperm

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16
Q

Prinicpal cells in the epididymis function to…

A

reabsorb fluid
secrete glycosylated products that aid in sperm maturation
partiticpate in decapitation

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17
Q

Cells in the epididymis are sensitive to…

A

androgens

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18
Q

Decapacitation factor

A

Blocks binding of sperm to ZP

Blocks fertilization

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19
Q

Decapitation

A

Addition of decapacitation factor in the epididymis to block fertilization

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20
Q

Capacitation

A

Removal of decapacitation factor in the female reproductive tract to permit fertilization

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21
Q

Sperm exit the epididymis into the…

A

vas deferens

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22
Q

The vas deferens joins with the _ duct near the bladder to form the _.

A

Seminal vesicle
Ejaculatory Duct

23
Q

What is the flow of semen production?

A

Testes → seminiferous tubule → straight tubule → rete testis → efferent ductules → epididymis → vas deferens → vas deferens joins seminal vesical → ejaculatory duct → prostate → urethra

24
Q

What is the function of the vas deferens?

Vas deferens = Ductus Deferens

A

Carry sperm through the spermatic cord to prostatic urethra

25
What epithelium lines the vas deferens?
Pseudostratified columnar epithelium with stereocilia
26
What differentiates the vas deferens from the epididymis?
Thick muscular layer (2-3 layers)
27
What are the three muscular layers of the vas deferens?
Inner longitudinal Middle circular Outer longitudinal
28
Pampiniform plexus
Found near the vas deferens Veins with bundles of longitduinal muscle in the tunia intima and tunica adventitia
29
Vas deferens histologically
Pseudostratified columnar epithelium Inner longitudinal Middle circular Outer longitudinal Pamipiniform plexus nearby
29
Where is the prostate gland located?
Wrapped around the urethra
30
What is the function of the prostate gland?
Releases product into the urethra
31
What is the product released from the prostate gland into the urethra?
Slightly alkaline fluid that contains enzymes that maintain seminal fluid as liquid
32
Does prostate disease effect urethral function? Why or Why not?
Yes The prostate surrounds the urethra so inflammation or hypertrophy can impact urethral function
33
What are symptoms of prostate disease?
Difficulty urinating (starting, volume, incomplete voiding, pain)
34
Inflammation of the prostate in what zones impacts the urethra?
Transitional zone Periurethral zone
35
Inflammation in which zone does not impede the function of the urethra?
Peripheral zone
36
Why does prostate cancer usually not impact urethra function?
It usually appears in the peripheral zone
37
Prostate histology
Urethra in center Glandular tissue pseudostratified to stratified squamous epithelium in lumen Fibromuscular stroma Secretory/Ducts Corpora Amylacea
38
Fibromuscular Stroma
Smooth muscle mixed with collagen fibers
39
How is the Corpora Amylacea formed?
Prostatic secretions percipitate out
40
Function of the seminal vesicle is controlled by...
testosterone
41
What is the seminal vesicle?
Paired, elongated highly folded tubular glands
42
Describe the wall of the seminal vesicle
Wall has mucosa (pseudostratified columnar with lamina propria) Thin layer of smooth muscle fibrous coat
43
How many lumens does the seminal vesicle have?
Single lumen but folds make it look like many lumens histologically
44
What are mucosal crypts?
The folds in the lumen of the seminal vesicle that make it look like it has multiple lumens
45
What is secreted from the seminal vesicle?
Viscous liquid contains fructose (metabolic subtrate for sperm), other simple sugars, amino acids, asorbic acid and prostaglandins
46
In the seminal vesicle, lamina propria is most visible in the...
mucosal crypts
47
Tunica albuginea in the penis
Dense CT and corpus cavernosum
48
Corpus cavernosum
Single deep artery - may only see branches smaller arteries Cavernous sinus Erectile tissue
49
Corpus spongiosum
not a lot of blood space Immediately surrouds urethra Glands of littre
50
Erection Hydraulics
Blood travels into spaces in the corpora cavernosa → results in a build up of pressure
51
Penis histology
Skin Tunica Albuginea (dense CT) Corpora Canvernosa Corpus Spongiosum Urethra Helicinie Arteries w/ erectile tissue
52
Cavernous sinus
Found in the corpus cavernosum Space that fills with blood during erection
52
Glands of littre
Mucus secreting glands that secrete into urethra