The Kidney 1 Flashcards
list the components of the nephron
- glomerulus
- Bowman’s capsule
- proximal convoluted tubule
- loop of Henle
- distal convoluted tubule
what is the function of the afferent and efferent arterioles?
For each nephron, anafferent arteriole feeds a high-pressure capillary bed called the glomerulus.
Blood exits the glomerulus into theefferent arteriole. The efferent arteriole then forms a second capillary network around the tubule, called theperitubular capillaries.
Define filtration
Filtration allows substances to leave the circulation and enter the nephron
What is the glomerulus?
a tuft of capillaries that acts as a molecular sieve
what substances are filtered?
- excess water
- salts
- creatinine
- urea
what substances are not filtered?
blood cells and protein
define reabsorption
reabsorption allows substances to leave the nephron and re-enter circulation
define secretion
allows substances to leave the circulation and enter the nephron if they haven’t been filtered (some are filtered tho)
what does GFR stand for?
glomerular filtration rate
what pressures drive filtration?
glomerular capillary (hydrostatic) pressure -
glomerular capsule pressure
+ colloidal osmotic pressure
= net filtration pressure
how do the pressures drive the process of glomerular filtration?
The blood inside the glomerulus ->glomerular hydrostatic pressure which forces fluid out of the glomerulus into the glomerular capsule. The fluid in the capsule creates pressure pushing fluid out of the capsule -> glomerulus, opposing the glomerular hydrostatic pressure. This is thecapsular hydrostatic pressure. These fluids exert pressures in opposing directions.