The Immune System Flashcards
where are sites where immune responses can be mounted, and in which B-cells are activated?
Spleen and lymph nodes
MHC class I is present where? and displays what?
In all nucleated cells and displays endogenous antigen to cytotoxic T-cells (CD8+ cells)
MHC class II is present where? and displays what?
In professional antigen-presenting cells and displays exogenous antigen to helper T-cells (CD4+ cells)
What cells do natural killer cells attack?
Cells not presenting MHC molecules, including virally infected cells and cancer cells
Neutrophils
Ingest bacteria (opsonized); follow bacteria using chemotaxis
Eosinophils
Used in allergic reactions and invasive parasitic infections; release histamine
Basophils
Used in allergic reactions
Active vs. Passive immunity
Immunization is active, transfer of antibodies is passive