The Endocrine System Flashcards
Peptide hormones
polar, cannot pass through the plasma membrane
bind to extracellular receptors and use a second messenger
rapid and short lived
Steroid hormones
minimally polar
bind intracellularly and intranuclearly
slow, but long lived
must be carried by specific proteins
AA-derivative hormones
mix of both characteristics of peptide and steroid
GnRH
promotes the release of FSH and LH
GHRH
promotes the release of GH
TRH
promotes the release of TSH
CRF
promotes the release of ACTH
PIF (dopamine)
inhibits the release of prolactin
Tropic Hormones (FLAT)
FSH, LH, ACTH, TSH
Direct Hormones (PEG)
Prolactin, endorphins, GH
FSH
promotes the dev. of ovarian follicles in females and spermatogenesis in males
LH
promotes ovulation in females and testosterone prod. in males
ACTH
promotes synth. and release of glucocorticoids from the adrenal cortex
TSH
promotes synth. and release of T3 and T4
Prolactin
promotes milk prod.
Endorphins
decreases perception of pain and can cause euphoria
GH
promotes growth of bone and shunts glucose to these tissues
T3 & T4
Produced by follicular cells and contain iodine; increase basal metabolic rate
Calcitonin
Produced by parafollicular cells decreases plasma Ca2+ conc. decrease Ca2+ absorption in the gut, and promotes Ca2+ storage in bone
PTH
Released by parathyroid glands
- decreases excretion of ca2+ by the kidneys and increases bone resorption to increase blood Ca2+ conc.
- activates vit D
Adrenal cortex produces (3)
Glucocorticoids (cortisol and cortisone)
Mineralocorticoids (aldosterone)
Cortical sex hormones (androgens, estrogens)
Glucocorticoids
Increase blood glucose conc., reduce protein synthesis, inhibit immune sys, participate in stress response
Mineralocorticoids
promotes Na+ reabsorption in the DCT & collecting duct, bringing H2O in.
Adrenal medulla secretes
catecholamines
Pancreas hormones
Glucagon
Insulin
Somatostatin (inhibits glucagon and insulin secretion)
Gonads produce
testosterone from the testes
estrogen and progesterone from ovaries
Pineal gland releases
melatonin, which regulates circadian rhythms
stomach and intestinal cells produce
secretin, gastrin, and CCK
Kidneys produce
erythropoietin
Atria of the heart secretes
ANP
Thymus secretes
Thymosin (for proper T-cell dev.)