The Heart Flashcards
Where is the heart located?
Anterior portion of the mediastinum; immediately posterior to the sternum
What is the Mediastinum?
Region between the 2 pleural cavities. Contains the great vessels, thymus, esophagus and trachea
What are the 3 layers of the heart? (1)
Pericardium: the pericardial sac surrounds the heart. Consists of a dense network of collagen fibres. It stabilises the position of the heart and associated vessels within the mediastinum.
Pericardium is lined by a serous membrane that can be divided into 2 portions:
1) Visceral pericardium/epicardium: covers and adheres closely to the outer surface of the heart
2) Parietal pericardium: Lines the inner surface of the tough pericardial sac surrounding the heart
What is the pericardial cavity?
The space between the visceral and parietal layers of the pericardium.
Contains pericardial fluid; secreted by the pericardial membrane. Acts as a lubricant, reducing friction between the opposing surfaces of the heart beats.
Whats an infection of the pericardium called?
Pericarditis: inflammation of the pericardial surface - causes them to rub against one-another, making a distinctive scratching noise
What is the epicardium?
The visceral pericardium that covers the outer surface of the heart. This serous membrane consists of an exposed mesothelium and an underlying layer of loose areolar CT that is attached to the myocardium.
What is the myocardium?
The muscle wall of the heart, forms the atria and ventricles. It consists of concentric layers of cardiac muscle tissue.
What is the endocardium?
Layer covering the inner surfaces of the heart, including those of the heart valves. A layer of simple squamous epithelium is continuous with the endothelium of the attached great vessels.
Where is the apex beat found?
Left 5th intercostal space (important for measuring heart beat)
What are the functions and characteristics of the right atrium?
Function: Receives blood from the systemic circuit through the 2 great veins (superior and inferior vena cava)
Superior vena cava: opens into the posterior and superior portion of the right atrium : delivers blood from the head, neck, upper limbs and chest.
Inferior vena cava: opens into the posterior and inferior portion of the right atrium : delivers blood from the rest of the trunk, viscera and lower limbs
Posterior walls and interatrial septum are smooth. Anterior atrial wall and inner surface of the auricle contain prominent muscular ridges = PECTINATE MUSCLES
What is the Coronary sinus?
A large thin-walled vein that opens into the right atrium inferior to the connection with the superior vena cava.
The cardiac veins draining the myocardium return blood to the coronary sinus.
Whats the role of the right ventricle and what are its features?
Blood travels from the right atrium into the right ventricle through a broad opening bordered by 3 fibrous flaps (cusps) and they are part of the right atrioventricular valve (tricuspid valve)
The tricuspid valve closes when the right ventricle contracts, preventing the backflow of blood into the right atrium.
Its internal surface contains papillary muscles, conical muscular projections that arise from the inner surface of the right ventricle.
Contains a series of irregular muscular ridges: the trabeculae carneae.
The moderator band is a muscular ridge that extends horizontally from the inferior portion of the interventricular septum and connects to the anterior papillary muscle - contains part of the conducting system - delivers the stimulus for contraction to the papillary muscles - they begin tensing the chordae tendineae before the rest of the ventricle contracts.
Superior end of the right ventricle tapers to the conus arteriosus (cone-shaped pouch) that ends at the PULMONARY VALVE/PULMONARY SEMILUNAR VALVE
What are chordae tendineae? What are is their importance in regards to blood flow?
The free edges of the tricuspid and bicuspid valves are attached to CT fibres called chordae tendineae; fibres which originate at the papillary muscles.
Papillary muscles are conical muscular projections that arise from the inner surface of the ventricles - without them, the cusps would be like swingin doors that permit bloodflow in both directions. The musles contract and begin tensing the chordae tendineae - preventing backflow.
What are the right and left ventricles separated by?
Interventricular septum
Where does the blood in the right ventricle flow to when it contracts?
As it contracts the pulmonary valve (3 semilunar cusps of think CT) passes through this valve and into the pulmonary trunk, the start of the pulmonary circuit.
Once in the trunk, blood flows into the left pulmonary left and right pulmonary arteries (deoxygenated). These vessels branch repeatedly within the lungs before supplying capillaries, where gas exchange occurs.
What are the features of the left ventricle and what is its role?
From the respiratory capillaries, blood collects into small veins (oxygenated) that unite to form the 4 pulmonary veins.
The posterior wall of the left atrium receives oxygenated blood from 2 left and 2 right pulmonary veins.
- It has an auricle
- it has a left atrioventricular valve (bicuspid/mitral valve), which guards the entrance to the left ventricle. Allows blood flow into the left ventricle and prevents backflow when the left ventricle contracts.
What are the features of the left atrium and what is its role?
From the respiratory capillaries, blood collects into small veins (oxygenated) that unite to form the 4 pulmonary veins.
The posterior wall of the left atrium receives oxygenated blood from 2 left and 2 right pulmonary veins.
- It has an auricle
- it has a left atrioventricular valve (bicuspid/mitral valve), which guards the entrance to the left ventricle. Allows blood flow into the left ventricle and prevents backflow when the left ventricle contracts.
- Forms most of the base of the heart
What are the features of the left ventricle and what is its role?
Even though the ventricles hold and pump the same amount of blood, the left ventricle has thicker walls - due to having to push blood through the large systemic circuit.
- Doesn’t have a moderator band
- Trabeculae carneae are prominent
- 2 large papillary muscles tense the chordae tendineae that anchor the bicuspid valve and prevent blood backflowing into the left atrium
Where does the blood go after left ventricle contraction?
Blood leaves the ventricle through the Aortic valve and goes into the ascending aorta.
Once its left for the systemic circuit, the aortic valve prevents blackflow into the left ventricle - from here it flows into the aortic arch and into the descending aorta
What is Atrial and Ventricular septal defect (ASD & VSD)?
Holes in the septum between the two atrium or two ventricles - leads to insufficient blood circulation
What does Automaticity mean?
Contracting without neural or hormonal stimulation. The cardiac muscle possesses this property.
The cells that initiate and distribute the stimulus to contract are part of the heart’s conducting system aka the cardiac conduction system or nodal system
What are the 3 main elements of the conducting system? (1)
Sinoatrial (SA) node: located in the wall of the right atrium
What are the 3 main elements of the conducting system? (2)
Atrioventricular (AV) node: located at the junction between the atria and ventricles
The AV node is a collection of specialised cells that form the beginning of the atrioventricular bundle; extends the excitatory impulse to all ventricular musculature.
Atrioventricular Bundle:
- Follows along the lower border of the membranous part of the interventricular septum before splitting into right and left bundles.
Right bundle branch = continues on the right side of the interventricular septum toward the apex of the right ventricle. From the septum, it enters the septomarginal trabecula to reach the base of the anterior papillary muscle. It then divides and is continuous with the final component of the cardiac conduction system, the Purkinje fibres
Left bundle branch = Passes to the left of the muscular interventricular septum and descends to the apex of the left ventricle. Gives off branches which eventually become continuous with the purkinje fibres.
What are the 3 main elements of the conducting system? (3)
Conducting cells: Interconnect the two nodes and distribute the contractile stimulus throughout the myocardium. Thought to be specialised myocytes
In the Atria, conducting cells are found in INTERNODAL PATHWAYS, which distributes the contractile stimulus to atrial muscle cells as this electrical impulse travels from the SA node to the AV node.