The Heart Flashcards
Flow of blood inside the heart
Deoxygenated blood returns from the body in the vena cava and enters the right atrium
The blood then passes through an atrioventricular valve into the right ventricle and then out through the semi lunar valve into the pulmonary artery
The blood now passes through a second atrioventricular valve into the left ventricle and then through the semi lunar valve into the aorta, and then onto respiring body tissues
Pressure in the heart chambers
The atria fill with blood as the pressure in them increases
The atria systole pushing the atrioventricular valves open and pushing blood into the ventricles
High pressure in the ventricles causes the atrioventricular valves to shut
The ventricles systole pushing the semilunar valves open, pushing blood out of the heart
The deoxygenated blood travels to the lungs via the pulmonary artery and the oxygenated blood travels to the body via the aorta
What do systole and diastole mean?
Systole- contraction of heart muscle
Diastole - heart muscle relaxes
Aneurysm
When the artery becomes blocked, blood flow through the area is restricted
The blood pressure builds up in front of the blockage and presses on the artery wall
This pressure causes the wall to weaken and it starts to bulge outwards
This is known as an aneurysm. The vessel may rupture, causing internal bleeding
Atherosclerosis
Process of atheroma formation
Plaque builds up under artery walls until it blocks half of the artery lumens, due to artery damage and lipid accumulation
Thrombosis
Plaque breaches epithelium, causing a blood clot
If the thrombus can move it can cause blockages elsewhere which can lead to apoptosis (cell death)
Myocardial infarction (heart attack)
Plaque builds up and completely covers artery
This causes a heart attack as cells cannot respire.
Artery adaptations
Thick muscular wall - helps to withstand high pressure
Elastic fibers - helps them to stretch and recoil
Arterioles - slow the flow of blood as capillaries are delicate but also to give time for substance exchange
Vein features/adaptations
Easily ruptured
Less muscle - less pressure to withstand
Large lumen - less pressure so veins push blood through as quickly as possible
Capiliary
One cell thick - short diffusion distance
Squamous (flattened cells). SA:V
Narrow lumen increases time for gas exchange
Calculating cardiac output
Cardiac output = stroke volume x heart rate
Why would heart rate need to increase/decrease?
Decrease:high blood pressure
To remove waste products from respiration
Lactic acid from anaerobic respiration needs to be delivered to the liver to be broken down
Increase
During fight/flight/exercise
Non modifiable risk factors for cardiovascular disease
Age
Gender
Race and ethnicity
Genetics
Modifiable risk factors for cardiovascular disease
high BP
smoking
physical activity
obesity
high blood cholesterol
The cardiac cycle - Diastole
Atria and ventricular muslces relax
Blood enters the atria via the vena cava and pulmonary vein
Blood flowing into atria increases pressure within atria