Enzymes Flashcards
What is an enzyme
An enzyme speeds up the rate of a chemical reaction and enables metabolic reactions to occur without being used up
They do this by lowering the activation energy through forming enzyme substrate complexes
Describe the induced fit model
Substrate enters enzymes active site and is not yet complimentary
Binding of the substrate molecule induces the change in the shape of the active site, so it is now complimentary to the substrate.
As the active site changes shape it causes distortion in the substrate
When the substrate leaves the active site the active site then returns to its previous state
Effect of temperature on enzymes
As the temperature increases the molecules have more kinetic energy so there are more successful collisions and therefore an increased rate of reaction
However above the optimum temperature high kinetic energy causes amino acids in polypeptide chain to be broken
This breaks hydrogen and ionic bonds between the R groups, the tertiary structure is therefore lost