The Gastrointestinal System Flashcards
What are the four main components of the digestive system?
- GI tract
- Pancreas, gall bladder, liver
- Enzymes, hormones, nerves, blood
- Mesentery – tissue that supports digestive organs
Outline the process of digestion
- saliva produced in response to food
- churning and mixing with saliva turns food into bolus.
- Saliva breaks down starch/sugar.
- bolus passes through esophagus to the stomach.
- Stomach nerves sense food and trigger peristalsis.
- Stomach mixes and churns bolus with acid and enzymes that break down proteins. This stimulates the pancreas, liver, and gallbladder to produce digestive juices. Bile secreted by the gallbladder.
- bolus moves into small intestine, where bile is secreted by the gall bladder.
- The duodenum dissolves fats to be digested by pancreatic juices and bile. Carbs get converted into glucose, fats to triglycerides and fatty acids, and proteins into amino acids.
- Enzymes are absorbed into the ilium
- water, fibre, and waste move into the colon and body signals defecation.
Total Parenteral Nutrition
nutrition delivered intravenously
- contains dextrose, amino acids, electrolytes
Indications: enteral nutrition is contraindicated or the patient is unable to tolerate; increased aspiration risk; GI obstruction
Complications: infection (change bag and tubing q24h; refrigerate until hanging bag), fluid overload (daily weights; check lytes), hyper/hypoglycemia (don’t stop abruptly; give 10% dextrose if bag runs out; titrate when turning up or down; check BG q4-6h); embolism.
Laxatives
Action: Produce immediate BM
Examples: Lactulose, bisacodyl, milk of magnesia, PEG, Senna
Stool Softeners
Action: pulls water into the GI tract
Example: Docusate
Antidiarrheals
Loperamide
Diphenoxylate
Bismuth
Antiemetics: Ondansteron
Indication: nausea, vomiting
Action: blocks effects of serotonin on the vagal nerve and CNS
Considerations: administer slowly; fast IV push can cause prolongation of QT interval and ventricular tachycardia.
Antiulcer Agents
H2 Receptor Blockers
PPIs
Antacids
GI protectants
Famotidine
Pharm Class: H2 Receptor Blocker
Action: blocks release of histamine and gastric acid secretion
indication: GERD; hypersecretory conditions; GI distress
Considerations: monitor kidney function and CBC; use short term.
Omeprazole
Pharm Class: PPI
Indications: GERD and ulcers
Action: Prevents H+ transport into gastric lumen; decreases gastric acid secretion production.
Considerations: administer 30-60 mins before meals; report black, tarry stools ( ulceration may cause bleeding).
Sucralfate
Indication: Ulcers; GERD
Action: promotes healing by providing a barrier and binding to proteins excreted by damaged ulceration tissue.
Considerations: avoid antibiotics for 2 hours; may decrease bioavailability of warfarin, digoxin, phenytoin, and levothyroxine; take on empty stomach; avoid antacids within 30 mins; caution with renal failure; monitor BG in diabetics.
Nasogastric Tube
tube inserted into the nare that terminates in the stomach
Indication: enteral nutrition, decompression, med amin, removal of stomach contents following overdose.
How is placement for NG tube verified?
chest x-ray
May also test residuals for pH (If residuals more than 500mL, hold the feed)
Blakemore tube
tube inserted into the esophagus to the stomach that balloons to stop bleeding along the esophagus
Considerations: keep scissors at bedside.
Function of the small intestine
absorbs nutrients
churns and mixes digested foods with mucous and enzymes, creating chyme; receives digestive juices from pancreas and liver.
Function of the large intestine
absorbs H20 and electrolytes; produces and absorbs vitamins; forms and propels feces towards the rectum
Ulcerative Colitis
inflammation of the large intestines, producing ulcerated surfaces that appear to be patchy
Crohn’s Disease
Inflammation and erosion of the ileum and anywhere else throughout the small intestine and large intestine.
Treatment for Crohn’s
LOW Fibre diet*
avoid hot/cold foods
steroids
no smoking
antidiarrheals
antibiotics
severe cases may involve removing portion of intestine with ostomy for relief.
Appendicitis
inflammation of the appendix
Signs and Symptoms of Appendicitis
pain begins with full, steady periumbilical pain
over 4-6 hrs, pain progresses and localizes to RLQ pain
nausea, vomiting
increased temperature
anorexia
increased WBC
Sudden relief may indicate burst appendix, which can lead to peritonitis
McBurney’s Sign (rebound tenderness of RLQ)
Pre-op positioning for appendectomy
no heat (induces rupture)
right-sided fowlers
Post-op Appendectomy Care
IV ABx
Pain management
NPO until return of bowel sounds
wound care
Endocrine Function of the pancreas
regulates blood glucose by releasing insulin and glucagon
Exocrine function of the pancreas
secretes tyrupsin, amylase, lipase, into the duodenum to digest carbs, fats, and proteins.
Pathophysiology of pancreatitis
digestive enzymes activate inside the pancreas, causing auto digestion of the pancreas; prevents secretion of digestive enzymes into the common bile duct, producing abdominal pain.
Signs and Symptoms of Pancreatitis
pain that increases with food intake
abdominal distention
ascites
rigid abdomen
Turner’s Sign (discolouration of the flank)
Nausea Vomiting
Jaundice
Hypotension
Bruising over flank/side
Treatment for Acute Pancreatitis
Labs: WBC, lipase
NPO
IV Fluids
Pain control (dilaudid)
Antispasmodic drugs to reduce gut motility
calcium replacement
TPN (promotes pancreatic rest)
electrolyte replacement
antibiotics for fever
Corticosteroids
Liver Function
produces bile, albumin, cholesterol; converts glucose into glycogen fro storage; converts ammonia to urea; metabolizes bilirubin in the breakdown of RBC; metabolizes drugs and toxins; produces clotting factors and regulates blood clotting.
Complications of cirrhosis
liver failure
Transmission of hepatitis A
fecal/oral
Transmission of hepatitis B
Body fluids
Transmission of hepatitis C
Body fluids and contact with dirty medical equipment
Transmission of hepatitis D
contact with infected body fluids (must already have Hep B)
Transmission of Hepatitis E
Fecal/oral
Treatment of Hepatitis A
supportive care
Treatment of Hepatitis B
Acute = supportive
Long-term = antiviral treatment
Treatment of Hepatitis C
Direct-acting antivirals
Treatment of Hepatitis D
no treatment
Treatment for Hepatitis E
supportive
Health promotion for Hep A
vaccination and hygeine
health promotion for Hep B
vaccination, blood screening, hygeine
health promotion for Hep C
Blood screen, sanitary healthcare environment.
health promotion for Hep D
blood screen; use of sterile needles
health promotion for Hep E
improved hygeine and sanitation.
Cirrhosis
disease of the liver caused by chronic alcoholism or acute hepatitis; marked by degeneration of liver cells, inflammation, and fibrous thickening of tissue; cells are replaced with scar tissue; impairs blood flow, leading to portal hypertension
Assessment of Patient with Cirrhosis
palpable, firm liver
abdominal pain
dyspepsia
decreased serum albumin
ascites
splenomegaly
increased AST/ALT
dysfunction of clotting factors (increased risk for bleeding)
risk for anemia
fatigue
nausea/vomiting
spider veins
Treatment for Cirrhosis
Antacids
vitamins
diuretics
paracentesis
low protein, low sodium diet
daily weights
strict ins/outs
bleed precautions
skin care
be careful with drug doses
Total Parenteral Nutrition Indications
Enteral nutrition contraindicated
client not tolerant of enteral nutrition
high risk for aspiration
GI obstruction
Complications of TPN
infection
fluid overload
hypo/hyperglycemia
embolism
BG collection
✓ When collecting capillary blood glucose (CBG), the glucometer should be calibrated and in good working order
✓ CBG specimens should be collected from the lateral side of a finger that has been cleaned with isopropyl alcohol
✓ If a client is critically ill with a low hematocrit level, receiving vasopressors, or hypotensive, the CBG result may be inaccurate
Prednisone decreases the absorption of which electrolyte?
calcium; reduces serum calcium levels in patients with hyperparathyroidism
Causes of hypocalcemia
Celiac; Crohn’s; hypoparathyroid; hyperphosphatemia; alcoholism; malnutrition; malabsorption; pancreatitis
How does hypoparathyroidism cause hyperphosphatemia and hypocalcemia?
Hypoparathyroidism is a cause of hyperphosphatemia. The client who experiences hypoparathyroidism has too little parathyroid hormone (PTH). PTH regulates the serum calcium concentration through its effects on the bones, kidneys, and intestines. When there is too little PTH, there are decreased calcium levels (hypocalcemia). Since calcium and phosphorus have an inverse relationship, when there are low levels of calcium there are high levels of phosphorus. Thus, hypoparathyroidism causes hyperphosphatemia.
Determine the syndrome indicated by the following labs:
HA1C - 5.9%
BP – 155/82
Cholesterol – 218
BMI – 27
This client is showing evidence of metabolic syndrome and needs prompt intervention to mitigate the risk of diabetes mellitus. Nutritional intervention is necessary because this client needs to modify their diet and reduce their intake of sodium, fats, and simple carbohydrates. Thus, it would be appropriate for the nurse to initiate a referral to a registered dietician.
Metabolic Syndrome
Metabolic syndrome is when the client has three out of the five abnormalities –
✓ Hypercholesterolemia (> 200 mg/dl)
✓ High triglycerides (> 150 mg/dl)
✓ High fasting blood glucose (>100 mg/dl)
✓ Abdominal obesity (> 40 inches in men; > 35 inches in females)
✓ Elevated blood pressure (> 130/85 mmHg)
✓ Low High-Density Lipoproteins (<50 mg/dl)
Assessment Criteria for TPN
The assessment criteria used to determine the need for total parenteral nutrition (TPN) include an inability to achieve or maintain enteral access. Examples include motility disorders, intractable diarrhea (Choice A), impaired absorption of nutrients from the gastrointestinal tract (Choice B), and when oral intake has been inadequate for a period over seven days. TPN promotes tissue healing and is an excellent choice for a patient with burns who has an improper diet. Please note that oral intake is the best feeding method; the second best method is via the enteral route. Total parenteral nutrition (TPN) is indicated only in specific cases. TPN provides calories, restores nitrogen balance, and replaces essential fluids, vitamins, electrolytes, minerals, and trace elements. It provides the bowel a chance to heal and reduces activity in the gallbladder, pancreas, and small intestine. TPN can also promote tissue and wound healing and healthy metabolic function. TPN may be used to improve a patient’s response to surgery. TPN is a highly concentrated, hypertonic nutrient solution. Hence, it is given intravenously through a central venous access device, such as a multi-lumen, tunneled catheter into the subclavian vein, or a peripherally inserted central catheter (PICC). Strict surgical asepsis should be followed due to the risk of infections.
Appendicitis Assessment
Pain in right lower quadrant
anorexia
increased WBC and temperature
Nausea
McBurney’s Sign/Psoas
Pain begins as dull, steady periumbilical pain that progresses over 4-6 hrs and localizes
sudden relief may indicate rupture, which increases risk for peritonitis
Endoscopic retrograde cholangiopancreatography (ERCP)
Endoscopic retrograde cholangiopancreatography (ERCP) has a procedure that has lost popularity in the years because of the risk of post-procedure pancreatitis. This procedure aims to examine the biliary tree for obstruction or inflammation.
➢ This procedure involves moderate sedation, which requires the client to be NPO for six to eight hours prior to the procedure
➢ The client may be repositioned during this procedure to enhance the visualization of the structures
➢ Abdominal cramping immediately following this procedure is likely because of the gastric insufflation of carbon dioxide
➢ The client should be educated on any signs of pancreatitis, which includes nausea, vomiting, and/or abdominal pain
➢ Other complications include infection, bleeding, or perforation
immediate interventions for DKA
For a client with DKA, the immediate need should focus on restoring the depleted fluid volume caused by hyperglycemia (polyuria). Additionally, regular insulin intravenously is prescribed to correct the acidosis and hyperkalemia. During the infusion of regular insulin, the client should be monitored for hypoglycemia and hypokalemia.