The Extracellular Environment

Question 1

The earliest multicellular life evolved 600M years ago.

Answer 1

METAZOANS

Question 2

It is made-up of proteins and carbohydrates. It helps regulate important function like cell movement, growth, and communication.

Answer 2

Extracellular Matrix

Question 3

It is the outer surface of plasma membrane. It is consisting of carbohydrates that attached to proteins or lipids. Sugary Coating.

Answer 3

Glycocalyx

Question 4

A 50 to 200 nm thick sheet that surrounds the nerve fibers, muscle and fat cells making it safe.

Answer 4

Basal Lamina

Question 5

What are the four major components of ECM?

Answer 5

Collagens
Proteoglycans
Fibronectin
Lamini

Question 6

Composed of fibrous glycoproteins that are only in ECM. Has tensile strength.

Answer 6

Collagens

Question 7

Collagens are primarily produced by?

Answer 7

Fibroblast

Question 8

What do you call to overproduction of collagen?

Answer 8

Fibrosis

Question 9

A component wherein the core protein is attached to long chain of carbohydrates (sugar) called glycosaminoglycans.

Answer 9

PROTEOGLYCANS

Question 10

A large glycoprotein that plays an important role in cell adhesion, migration and differentiation.

Answer 10

Fibronectin

Question 11

A zinc containing enzyme that breaks down the materials outside the cell.

Answer 11

Matrix Metalloprotenase

Question 12

Made up of proteins that are connected by disulfide bond.

Answer 12

Laminin