The Experiment of Forssman

Question 1

What is the source of the antigen used in the Forssman experiment?

A) Sheep
B) Guinea pig
C) Rabbit
D) Human

Answer 1

B) Guinea pig

Question 2

Which antibodies are formed as a result of the Forssman experiment?

A) Anti-Rabbit cells
B) Anti-Human cells
C) Anti-Guinea Pig cells and Anti-Sheep cells
D) Anti-Sheep cells only

Answer 2

C) Anti-Guinea Pig cells and Anti-Sheep cells

Question 3

In the context of the Forssman experiment, what is the term “Forssman Antigen” used for?

A) Any substance that stimulates the formation of anti-Rabbit cells
B) Any substance that stimulates the formation of anti-Human cells
C) Any substance that stimulates the formation of sheep hemolysin (anti-sheep cells)
D) Any substance that stimulates the formation of guinea pig hemolysin (anti-guinea pig cells)

Answer 3

C) Any substance that stimulates the formation of sheep hemolysin (anti-sheep cells)

Question 4

What are “Heterophil Antibodies” in the context of the Forssman experiment?

A) Antibodies produced by unrelated species that can cross-react with different antigens
B) Antibodies that only react with guinea pig cells
C) Antibodies produced by the same species that can cross-react with different antigens
D) Antibodies that are only formed in rabbits

Answer 4

A) Antibodies produced by unrelated species that can cross-react with different antigens

Question 5

What is the main outcome of the Forssman experiment in terms of antibody formation?

A) Formation of Anti-Human cells
B) Formation of Anti-Sheep cells
C) Formation of Anti-Guinea Pig cells
D) Formation of Anti-Rabbit cells

Answer 5

C) Formation of Anti-Guinea Pig cells

Question 6

Which type of heterophil antibodies reacts with sheep cells, ox cells, horse cells/beef cells (-), but not guinea pig cells, and is not Forssman in nature?

A) Heterophil Antibodies in IM
B) Heterophil Antibodies of Forssman
C) Heterophil Antibodies in Serum Sickness
D) None of the above

Answer 6

A) Heterophil Antibodies in IM

Question 7

What type of heterophil antibodies reacts with Guinea pig cells, horse cells, and sheep cells (+) but not with ox or beef cells (-)?

A) Heterophil Antibodies in IM
B) Heterophil Antibodies of Forssman
C) Heterophil Antibodies in Serum Sickness
D) None of the above

Answer 7

B) Heterophil Antibodies of Forssman

Question 8

Which type of heterophil antibodies is positive with all four cells (sheep, ox, horse, guinea pig), and can be used as control?

A) Heterophil Antibodies in IM
B) Heterophil Antibodies of Forssman
C) Heterophil Antibodies in Serum Sickness
D) None of the above

Answer 8

C) Heterophil Antibodies in Serum Sickness

Question 9

Note that Guinea pig cells and ox cells are ______________________ ?

Answer 9

* Useful to differentiate these types of antibodies