Hepatitis B- only the DNA type of virus Flashcards
What is another name for Hepatitis B?
- Aka: serum hepatis or Dane particle.
Which family does Hepatitis B belong to?
- It belongs to the Hepadnaviridae family.
What type of infection does Hepatitis B cause, and which organ does it primarily affect?
- Viral infection that primarily attacks the liver (hepatocyte), causing both acute and chronic diseases. = more sever and fetal than HAV
How does the incubation period for Hepatitis B typically range?
- Ranges from 45 to 160 days, with an average of 120 days.
What is the genetic nature of the Hepatitis B virus?
- Hepatitis B is a double-stranded DNA virus.
What is the mode of transmission for a hepatitis B that resembles HIV and can be contracted through various means?
The mode of transmission for a disease resembling HIV includes contact with infectious blood, semen, and other body fluids. This can occur through:
a. Birth to an infected mother
b. Sexual contact with an infected person
c. Sharing of contaminated needles, syringes, or other injection drug equipment
d. Needle sticks or other sharp instrument injuries
What is the family of viruses to which Hepatitis B belongs?
- Hepatitis B is a DNA virus of the hepadnaviridae family of viruses.
What is the previous name for HBsAg?
- HBsAg was previously known as the “AUSTRALIA ANTIGEN.”
What does the presence of HBsAg indicate regarding HBV infection?
- An active infection, either acute or chronic.
When is HBsAg the best indicator of infection with hepatitis B?
- Chronic or acute infection with hepatitis B.
How is HBsAg used as a marker screen for patients?
- To assess if a patient has had a previous infection with hepatitis B or has not yet been exposed to hepatitis A or B.
Why is it important to test for HBsAg in patients?
- Assess whether a patient needs to receive the hepatitis B vaccine or a booster shot
Where is HBcAg typically found within the HBV?
- HBcAg is found within the core of the intact HBV or viral agent.
Why is HBcAg not detectable in serum?
- Because it is exclusively found in liver cells (hepatocytes) and tissues. Detecting it would require a liver biopsy.
Is HBcAg routinely tested in hepatitis profile testing?
- No, HBcAg is not routinely tested in hepatitis profile testing