The Endocrine System Flashcards
What are exocrine glands
Glands that secrete their products into ducts
What are endocrine glands
Ductless and release hormones into the blood
What are hormones
Hormones are chemical messengers carried by the blood to target cells
What does the endocrine system consist of
Glands and organs that secrete hormones
What are the functions of hormones
Regulation
Control growth and development
Regulate operation of the reproductive system
Help establish circadian rhythm
What are the 3 major structural classes of hormones
Amines
Peptides and proteins
Steroids
Examples of amines
Thyroid hormones
Dopamine
Catecholamines (epinephrine and norepinephrine)
Examples of peptides and proteins
The majority of hormones are peptides eg, insulin
Examples of steroids
Aldosterone
Cortisol
Androgens (testosterone)
Estrogens
How are peptide and catecholamine hormones transported
They are water soluble so therefore circulate dissolved in the plasma
Some peptide hormones bind to plasma
How are steroid and thyroid hormones transported
They circulate mainly bound to plasma proteins
Which organs remove hormones from the plasma
The liver and kidneys
By metabolising or excreting them
Where are receptors for steroid and thyroid hormones
Inside target cells
Where are receptors for peptide hormones and catecolamines
On the plasma membrane
What does the responsiveness of a target cell depend on
1) the hormone’s concentration in the blood
2) the abundance of the target cells hormone receptors
3) influences exerted by other hormones
What effects can hormonal interactions have
- permissive
- synergistic
- antagonistic
What inputs control hormonal secretion
1) plasma concentration of anion or nutrient that the hormone regulates
2) neural input to the endocrine glands
3) other hormones
What is a hormone that stimulates the secretion of another hormone referred to
A tropic hormone