The Chemical Senses Flashcards

1
Q

Trigeminal system
Function
Location
Receptors

A

Function: Detect noxious and irritating compounds
Location: Tongue, mouth, mucus membranes
Receptors: Trp family of ion chanals

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2
Q

Pathway of the olfactory system

A
  1. Olfactory receptor cells
  2. Olfactory Bulb
    • Axons from glomerulus
    • Mitral cells
  3. Olfactory Tract
  4. Olfactory Tubercle
  5. Pyriform Cortex
  6. Entorhinal cortex
  7. Amygdala
  8. Thalamus
  9. Frontal lobe
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3
Q

Locus cerulus

A

Sense of smell when hungry

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4
Q

Adrenergic epithelium

A

Heightened smell during fear & excitement

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5
Q

Mechanism for olfactory system to discriminate smells

A

Spatial arrangement in nose = gas chromatography

Each receptor cell expresses a limited number of receptors from 1 specific gene

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6
Q

2 types of olfactory receptors

A

G protein

Phospholipase C to IP3 production to Ca enter

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7
Q

How is the identity of of olfactory stimulus conveyed in terms

A

Rate of firing of an AP

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8
Q

Which is more sensitive, gustatory or olfactory system?

A

Olfactory system

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9
Q

Posterior tounge

A

CN IX

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10
Q

Middle tounge

A

CN IX

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11
Q

Anterior tongue

A

CN VII

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12
Q

Papillae associated with CN IX

A

Circumvallate & foliate

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13
Q

Papillae associated with CN VII

A

Fungiform

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14
Q

Which papillae are not associated with a CN

A

Filiform

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15
Q

Na channels associated with

A

Salt and sour taste

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16
Q

G protein associated with

A

Sweet, bitter & umani

17
Q

Which taste channels are blocked by amiloride

A

Na channels associated with salty & sour

18
Q

Pathway for gustatory information

A

Taste receptors
Solitary Tract
Thalamus (Ventral Posterior Nucleus)
Temporal lobe

19
Q

Mechanisms for gustatory system discrimination

A

Identity of molecule
Concentration of the molecule
Pattern recognition

20
Q

Disorders associated with decreased olfactory sense

A

Atrophic rhinitis
DIabetes
Alzheimer’s Disease

21
Q

Disorders associated with decreased olfactory & gustatory sense

A

Chronic renal failure

22
Q

Disorders associated with increased olfactory & gustatory sense

A

Epilepsy