The Cell Organelles Part 3 Flashcards

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1
Q

Which cytoplasmic organelles are membranous?

A

Mitochondria, Smooth&Rough endoplasmic reticulum, Golgi apparatus, lysosomes, peroxisomes, vesicles

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2
Q

Which cytoplasmic organelles are non-membranous?

A

Ribosomes, Centrioles, Cytoskeleton, Cilia, Flagella, Microvilli, Inclusions

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3
Q

Cytoskeleton

A

Has roles in cell movement, support and strength for the cell, phagocytosis, cytokinesis, cell-cell and cell-extracellular matrix adherence, and changes in cell shape

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4
Q

What is the cytoskeleton composed of?

A

The cytoskeleton is a complex network of microtubules, intermediate filaments, and microfilaments.

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5
Q

Microtubules

A

Composed of dimeric tubulin molecules and are structurally polarized with a plus end which in a low presence of a low Ca2+ concentration, guanosine triphosphate and Mg2+ grow more rapidly at the minus end

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6
Q

What are the three distinguishing factors of Alzheimer’s?

A

1) Accumulation of senile plaques B-amyloid accumulations
2) formation of numerous neurofibrillary tangles
3) Loss of cortical neurons particularly cholinergic neurons

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7
Q

Microtubular Functions

A

1) Intracellular vesicular transport
2) Movement of cilia & flagella
3) Attachment of chromosomes to the mitotic spindle
4) Cell elongation & movement
5) Maintenance of cell shape

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8
Q

Centrioles

A

Centrioles are cylindrical structures composed of short, highly organized microtubules. Centrosomes made of a pair of centrioles.

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9
Q

Cilia & Flagella

A

Cilia and flagella are motile processes covered by cell membrane with a highly organized microtubule core. The main function of cilia is to sweep fluid from the surface of cell sheets.

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10
Q

F-actin inhibitors

A

Cytochalasins- bind to fast growing end preventing further addition of G-actin. , Phalloidin- binds to actin filaments preventing depolymerization, Latrunculins- disrupt actin filaments by binding to G-actin an inducing F-actin deploymerization.

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11
Q

Intermediate Filaments

A

They provide mechanical support to cells. They lack polarity and do not require atp or gtp for synthesis.

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12
Q

Intermediate Filaments

A

The presence of a specific type of intermediate filament in tumors can reveal which cell originated the tumor information important for diagnosis and treatment.

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13
Q

Cytoplasmic deposits/ Inclusions

A

Usually transitory components of the cytoplasm, composed mainly accumulated metabolites or other substances.

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