the cardiac cycle Flashcards

1
Q

what are the 5 steps in the cardiac cycle?

A

The Cardiac Cycle:

[1] Late diastole —both sets of chambers are relaxed and ventricles fill passively.

[2] Atrial systole —atrial contraction forces a small amount of additional blood into the ventricles.

[3] Isovolumic ventricular contraction—ventricular contraction pushes AV valves closed & not enough pressure to open semilunar valves.

[4] Ventricular ejection—as ventricular pressure rises and exceeds the pressure in the arteries, the semilunar valves open and blood is ejected.

[5] Isovolumic ventricular relaxation—as ventricles relax, pressure in ventricles falls. Blood flows back into the cusps of semilunar valves and snaps them closed.

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2
Q

what are the semilunar valves?

A

aortic valve and pulmonary valve.

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3
Q

what is the minimum blood volume in ventricles?

A

The minimum blood volume in ventricles = end-systolic volume (ESV) seen in the Isovolumic ventricular relaxation stage

→ 60ml of blood

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4
Q

what is the maximum blood volume in the ventricles?

A

Maximum blood volume in ventricles = end-diastolic volume (EDV) seen in Isovolumic ventricular contraction stage

→ 140ml of blood

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4
Q

state the meaning of systolic and diastolic pressure and their values:

A

Systolic pressure is the peak arterial pressure = 120 mmHg

Diastolic pressure is the minimum arterial pressure = 80 mmHg

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5
Q

state what diastole and systole mean:

A

diastole = filling phase

systole = ejection phase

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5
Q

what happens to the mitral and atrial valves when the left ventricle changes?

A

When the LV pressure exceeds the pressure inside the left atrium, the mitral valve closes.

When the LV pressure is below the pressure inside the left atrium, the mitral valve opens.

When the LV pressure is above the aortic pressure, the aortic valve opens.

When the LV pressure is below the aortic pressure, the aortic valve closes.

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6
Q

define the pulse pressure:

A

the difference between the systolic and diastolic pressure.

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7
Q

define the mean arterial pressure:

A

the average arterial pressure throughout the cardiac cycle.

  • the driving force pushing blood through the circulation
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8
Q

define the atrial pressures of an ECG:

A

a-wave → atrial contraction, which occurs right after the P wave on ECG.

c-wave → rises when ventricles contract, causing the mitral valve to bulge into the atrium, and descends when the aortic valve opens.

v-wave → blood flowing from the lung into the left atrium while the ventricles contract.

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9
Q

what is the ejection fraction?

A

the stroke volume (SV) divided by the end-diastolic volume (EDV)

EF = SV/EDV = usually around 2/3 in a healthy heart.

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10
Q

define the isometric contraction period:

A

the time between the closure of the atrioventricular valves and the opening of the semilunar valves.

Involves pressure going up in ventricles above the pulmonary trunk/aorta which pushes the semilunar valves open.

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11
Q

define the isometric relaxation period:

A

the time between the closure of the atrioventricular valves and the opening of the semilunar valves.

Involves pressure going up in ventricles above the pulmonary trunk/aorta which pushes the semilunar valves open.

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11
Q

what happens when the pressure within the ventricles drops below pressure in both the pulmonary trunk and aorta?

A

blood flows back toward the heart,
producing the dicrotic notch which is a small dip seen in blood pressure tracings.

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11
Q

when does the rapid and slow ejection phase occur?

A

rapid ejection phase occurs when the pressure rises in the ventricles enough to open the semilunar valves.

Occurs at the beginning of systole and involves a very quick drop in volume.

slower ejection phase occurs when the pressure falls in the ventricles until the semilunar valves close.

Occurs at the end of systole and involves a slower drop in volume.

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12
Q

when does the rapid and slow filling phase occur?

A

rapid filling phase occurs when the atrioventricular valves open and blood flows into the ventricles.

Occurs in early diastole and involves a very quick rise in volume.

slower filling phase occurs when the atrioventricular valves open and blood flows into the ventricles.

Occurs in late diastole and involves a very slow rise in volume.

13
Q

what causes the 4 heart sounds?

A

1st - closure of AV valves
2nd - closure of semilunar valves
3rd - rapid passive filling phase
4th - active filling phase

14
Q

state the causes of systolic murmurs (abnormal heart sounds):

A

Stenosis - unnatural narrowing of aortic/pulmonary valves

Regurgitation through mitral/tricuspid valves

14
Q

state the causes of diastolic murmurs:

A

Stenosis - unnatural narrowing of mitral/tricuspid valves

Regurgitation through aortic/pulmonary valves

14
Q

state the cause of a continuous murmur:

A

septal defect

14
Q

what is a phonocardiogram?

A

a plot of recording of the sounds and murmurs made by the heart.

15
Q

state where mitral and aortic murmurs radiate to:

A

Mitral murmurs radiate to the left axilla

Aortic murmurs often radiate to the left carotid artery

15
Q

Increasing the heart rate above 150 would affect the EDV

If EDV rises, SV rises because preload is greater.

Standing up reduces EDV because blood pools in the capacitance vessels

A