The Body And Drugs Flashcards

1
Q

Pharmacodynamics

A

Study of how drugs produce their effects on desired cells and how a drug is processed by the body

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Drug receptors can be compared to a

A

Lock

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Location where a drug will exert its desired effect

A

Site of action

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Mechanism of action (MOA)

A

Explains how a drug works and produces its desired effect on the body

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Receptor site

A

Where the drug binds to the cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Agonist

A

Specific type of dug that produces a certain and predicted action

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Antagonist

A

Drug that does not produce any noticeable or desirable effects of its own, but blocks other chemicals from attaching to a receptor cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Desired effect

A

Body’s response to a drug /intended response to a med

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Dose response curve

A

Indicates the body’s response to a drug is directly related to the amount of the drug taken

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Ceiling

A

Maximal response the body as to a drug

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

ED50

A

The measurement of the specific amount that is needed to achieve 50% of the maximal response

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Half-life

A

Time required for plasma serum concentration levels of an absorbed and distributed drug to decrease by one half

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Half life is written as

A

T1/2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Time response curve

A

Length of time in which a specific drug will continue to have same degree of effects

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Pharmacokinetics

A

Study of time course of a drug and its metabolites in the body following drug administration by any route

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Pharmacokinetics

A

Study of drug movement throughout the body

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Absorption

A

Process by which the drug is moved from its site of administration into the blood steam

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Intravenous

A

Type of drug administration that bypasses some of the aspects of absorption

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Distribution

A

Process that the drug is moved from the blood stream to the body tissue or receptors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Passive diffusion

A

Movement of a substance across a cell membrane

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Facilitated diffusion

A

A carrier protein permits specific molecules to pass though certain parts of the cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Pinocytosis

A

The cell engulfs the substance and permits the substance to enter the cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

More lipid soluble drug is the more. , the drug will be absorbed into a cell

A

Quickly

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Clearance

A

Time it takes a drug to be eliminated from the body

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Addiction
Pattern of compulsive substance abuse characterized by a continued psychological and physiological crabbing or need for the substance and its effects
26
Characteristics of addiction
Absorbed focus, painful withdrawal, damaging consequences
27
Number of Americans addicted to alcohol
14 million
28
Number of deaths associated with alcohol per year
100,000
29
Excessive alcohol drinking while taking warfarin can cause
Blood clots
30
Occasional alcohol drinking while taking warfarin can cause
Internal bleeding
31
Treatments for alcoholism
Disulfiram, acamprosate calcium, naltrexone
32
Drug treatments for smoking cessation
Bupropion, verenicline, nicotine polaerilex
33
Bioavailability
Degree to which a drug becomes available to tissues after administration
34
Metabolites
Any substance produced by the metabolic process
35
Excretion
Process by which drugs are eliminated from the body
36
A drug that is designed to produce an action rather than stop an action
Agonist
37
Drug works by blocking he action of a receptor
Antagonist
38
Potency is the measure meant of the ___ of the drug that is required to have a specific effect on the body
Strength
39
Chemicals that do not readily cross the cell membrane barrier
Ionized
40
Metabolism
Bio transformation
41
A drug that binds directly to cell membranes and is not absorbed by the body in any way
Metamucil
42
Facilitated diffusion
Type of drug transportation into the cell that does not require the cell to expand energy
43
When a chemical bind with a ______, it is stimulated to either produce or inhibit a specific action
Receptor
44
First pass process
Process which the liver begins the absorption of an oral medication
45
Maximal drug response to a drug reaches the ceiling, it can be toxic especially to
Liver and kidneys
46
Absorption
Process of movement of the drug from the circulatory system across airier membranes to the site of a drug action
47
Elimination
Process that results in removal of drug from the body and the discontinuation of the drug action
48
Metabolism
Biochemical process involving transformation of active drugs to a compound that can be easily eliminated or inactive drugs to active drugs
49
1 ml = gtt
120
50
5tbsp =. ml
25ml
51
120mg =. gr
0.120 gr
52
0.5 gr =. mg
500mg
53
10g =. mcg
10,000,000
54
8oz =. ml
236ml
55
44kg =. Lbs
96.8lbs
56
1pt =. Cc
473.17cc
57
2c =. Oz
16oz
58
1.5l =. Cc
1,500 cc
59
15tsp =. Oz
2.5oz
60
Target cell
Large number of cells all of which are similar to each other
61
Albumins and globulins
Proteins that help with transporting chemicals though the blood
62
Alcohol is a
Depressant