The Blood Chapter 19 Flashcards

1
Q

True or False: Blood Carry oxygen and carbon dioxide?

A

True

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2
Q

True or False: Blood does not transport nutrients and wastes.

A

False

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3
Q

True or False: Blood regulates water, electrolytes, and temperature

A

True

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4
Q

True or False: Blood does not have the ability to carry hormones

A

False, blood does carry hormones

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5
Q

True or False: Blood presents infections

A

True.

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6
Q

True or False: Blood does not assist in clothing and inflammation?

A

False

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7
Q

True or False: You have 5 quarts or 5 liters of blood?

A

True

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8
Q

True or False: Plasma Consists of %55 of blood when compared to formed elements that are 45%?

A

True

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9
Q

What is Serum?

A

Plasma but without clotting factors, it wont coagulate.

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10
Q

What is plasma composed of?

A
Water
Proteins
Nitrogenous molecules
Nutrients
Gases
Electrolytes
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11
Q

What does Albumin do?

A

Maintenance of blood volume and pressure, as well as transport of lipid substances.

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12
Q

True or False: Albumin is a carrier molecule?

A

True

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13
Q

True or False: Albumin is not synthesized in the liver?

A

False, Albumin is synthesized in the liver

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14
Q

True or False: Albumin is not a protein?

A

False, it is a Major protein

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15
Q

What does Globulin do?

A

Carry substances such as iron and bilirubin, as well as dealing with immunity.

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16
Q

True or False: Globulins control blood osmotic pressure and also a carrier molecule?

A

True

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17
Q

True or False: Platelets are part of form elements?

A

True

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18
Q

True or False: Red blood cells are not part of formed elements?

A

False

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19
Q

True or False: White blood cells are not part of formed elements?

A

False, they are.

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20
Q

What are formed elements composed of?

A

Platelets, white blood cells, and red blood cells.

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21
Q

True or False: Neutrophils are part of white blood cells?

A

True

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22
Q

True or False: Lymphocytes do not make up white blood cells.

A

False, they do make up white blood cells.

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23
Q

True or False: Monocytes do not make up white blood cells. Only neutrophils and lymphocytes make up white blood cells

A

False, Monocytes do make up white blood cells along with Neutrophils, lymphocytes, monocytes, eosinophils, and basophils.

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24
Q

True or False: Eosinophils make up while blood cells?

A

True

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25
True or False: Basophils do not make up white blood cells?
False they do.
26
What is white blood cells consist of?
``` Neutrophils 60-70% Lymphocytes 20-25% Monocytes 3-8% Eosinophils 2-4% Basophils 0.5-1.0% ```
27
What is Hematocrit?
The percentage of blood volume that is RBC.
28
True or False: Erythrocytes are RBC
True
29
True or False: White blood cells are leukocytes?
True
30
True or False: Platelets are Thrombocytes?
True
31
True or False: Mature RBC have a nucleus?
False, mature RBC do not have a nucleus.
32
True or False: RBC have no organelles and lack mitochondria?
True
33
True or False: You use glycoproteins and glycolipids to determine blood type?
True
34
True or False: RBS does not contain hemoglobin?
False
35
What does Hemoglobin do?
Carry oxygen and carbon dioxide
36
What is hemoglobin made of?
4 globin proteins and a heme center. The heme center is what holds your O and carbon.
37
What is polycythemia?
An excess of RBC
38
What is Anemia?
RBC or globin deficiency
39
What is sickle cell anemia?
Deformed RBC
40
What do Fribin and Thrombin do?
Deal with blood clotting
41
True or False: WBC contains a nucleus and organelles?
True
42
True or False: WBC do not lack hemoglobin
False they do lack hemoglobin
43
What are the 2 main groups of WBC?
Granulocytes and Agranulocytes
44
What are the 3 different types of granulocytes?
Neutrophils, eosinophils, basophils
45
What are the 2 types of agranulocytes?
Monocytes and lymphocytes?
46
True or False: Neutrophils are the most numerous?
True
47
True or False: Neutrophils do not consume bacteria
False, it does consume bacteria
48
True or False: Neutrophils phagocytes (engolf) bacteria
True
49
True or False: Neutrophils have many lobules
True
50
True or False: Eosinophils do not contain enzymes that destroy parasites?
False, they contain enzymes that destroy parasites and release enzymes that kill the parasites
51
True or False: Eosinophils may be involved with allergies?
True
52
What is the difference between the way Neutrophils and Eosinophils destroy bacteria?
Neutrophils engold and Eosinophils release enzymes
53
True or False: Basophils are the most numerous
False, they are the least numerous.
54
True or False: Basophils response to inflammation?
True
55
True or False: Basophils secrete histamine and heparin?
True
56
True or False: Monocytes are a phagocytic type of cell but are fixed?
True, they stay in their area
57
True or False: Monocytes are not agranular?
False, they are agranular
58
True or False: Monocytes do not have a viral response?
False, If you come in contact with a virus it sends out signals that there is a virus.
59
True or False: Monocytes do not consume neutrophils, pathogens, dead cells, bacteria.
False, they do
60
True or False: Lympocytes are the second numerous?
True
61
True or False: Lymphocytes are not agranular, do not have large nucleus, and little cytoplasm?
False, Lymohocytes are agranular, very large nucleus, little cytoplasm.
62
True or False: Lymphocytes do not develop from precursor stem cells?
False, they do develop from stem cells.
63
True or False: Lymphocytes can produce antibodies?
True, and also do a variety of killing.
64
True or False: Lymphocytes does not kill viruses, cancer, or foreign cells?
False
65
What is Leukocytosis?
Increase number of WBC
66
What is Leukemia?
Cancer of WBC
67
What is Leukopenia?
Decreased number of WBC
68
True or False: Platelets have an irregular shape, contain vesicles, and no nucleus?
True
69
True or False: Platelets have a long life span?
False, they have a short life span of 5-9 days
70
True or False: Platelets lack the chemical that promote blood clotting?
False it contains the chemicals that promote blood clotting.
71
True or False: Antibodies recognize antigens?
True
72
What are the 4 main blood types?
A, B, AB, O
73
True or False: AB contains both A and B antigens?
True
74
True or False: O contains all A,B,AB, and O antigens?
False, no antigens are present.
75
What is Rh factor?
Another type of antigen that is on the red blood cell. if you have the antigen you are going to be Rh + and if you dont you will be Rh -. Example A+ will have antigen A and Rh and if you are A- they dont have Ph you will have antigen A.
76
True or False: AB+ is the universal donor and O- is the universal receiver?
False, AB+ is the universal receiver and O- is the universal donor.
77
True or False: Agglutination is a reaction between proteins?
False, it is a reaction between antigen and antibody.
78
True or False: Agglutination occurs when the recipient receives the correct blood type?
False, agglutination occurs when the recipient receives the wrong blood type.
79
What is Agglutination?
Is a reaction between an antigen and an antibody. What happens is the blood cells clumps together. This happens when someone gives the wrong blood type to the individual.
80
True or False: Rh factor affects the second pregnancy when there is Rh- mother and a Rh+ fetus
True
81
What happens in the second pregnancy that would cause concern with Rh factor and is known as Erythroblastosis?
The mother creates antibodies against the fetus, causing agglutination within the fetus.
82
What is Hemopoiesis?
Production of formed elements
83
What is Erythropoiesis?
Production of RBC
84
What is Leukopoiesis?
Production of WBC
85
What is Thrombopoiesis?
Production of Plates
86
True or False: There are3 hemopoiesis that help with blood formation Which are Erythropoiesis, Lipids, Leukopoiesis?
False, it is Erythropoiesis, Leukopoiesis, Thrombopoiesis.
87
Where do Myeloid Stem cells form?
Forming within the red bone marrow
88
Where do Lymphoid hemopoiesis form?
From the lymoh tissues/ organs (thymus, tonsils, spleen). The lymphatic tissues.
89
True or False: Erythropoiesis is from the myeloid stem cell line?
True
90
True or False: the first step for Erythropoiesis is Reticulocyte?
False, that is the second to last in the process. the first is Proerythroblast.
91
True or False: the first step for Erythropoiesis is RBC erythrocyte.
False, it is the last step.
92
True or False: The first step in Erythropoiesis is Proerythroblast?
True, Kidneys secrete EPO receptor sends out signal to start creating RBC. Kidneys secrete EPO in response to hypoxia.
93
True or False: Erythroblasts is the second step in Erythropoiesis?
True, and during this step hemoglobin is produced.
94
True or False: Reticulocyte is the third step and the final RBC or Erythrocyte is produce?
True
95
True or False:The reticulocyte still have its nucleus?
True, reticulocyte is an immature RBC and will loose its nucleus. Once it leaves the bone marrow all ER is gone. The RBC will no longer have its nucleus.
96
What is the process of a RBC or Erythropoiesis?
1. From the Myeloid stem cell line 2. Proerythroblast 3. Erythroblasts 4. Reticulocyte 5. RBC
97
True or False: Leukopoiesis come from Lymphoid stem cell line and not from the myeloid?
False, it comes from both myeloid and lymphoid stem cell line.
98
True or False: Leukopoiesis froduce agranular leukocytes but not granular leukocytes?
False, it produces granular leukocytes and agranular leukocytes.
99
True or False: Leukopoiesis is colony stimulating factors (CSF) and interleukin stimulate WBC production?
True, say hey start creating more white blood cells.
100
True or False: Leukopoiesis have a short time life span
False, they have a long time frame where they can last for hours to decades.
101
True or False: Leukopoiesis leave blood to lymphatic system (recycled back to blood)
True
102
True or False: Thrombopoiesis produce RBC
False, they produce platelets.
103
True or False: Thrombopoiesis from from proteins?
False, they form from myeloid stem cell.
104
True or False: Thrombopoiesis form from megakarycocytes and fragment in the red bone marrow?
True
105
True or False: Megakaryocyte is the first stem in creating platelets?
False, it is the second.
106
True or False: Stem sell is the second step in creating plates?
False, it is the first step.
107
What are the stemps in Thrombopoiesis?
1. Stem Cell- Develop receptors for thromboipoietin (TPO)(produce in the liver) 2. Megakaryocyte- fpind in the bone marrow. 3. becomes platelets.
108
How long do RBC live for?
120 days
109
How are ruptured RBC removed?
Macrophages in spleen and liver
110
True or False: The intestines only absorb ferrous (Fe2+)
True
111
How are RBC disposed?
Many die in the spleen and liver and macrophages digest or heme and globin are recycled.
112
What is Hemolysis?
Ruptured RBC
113
How is Iron changed and and transported?
Intestines only absorb ferrous (Fe 2+) Stomach acids convert ferric (Fe 3+) to ferrous Transferrin transports iron to bone marrow via the liver Which finally used to manufacture hemoglobin Iron has to be changed to a different state and then be transported to the bone marrow.
114
True or False: Emigration is to stay and the white blood cells stay put?
False, it is to leave and the WBC must leave the bloodstream.
115
True or False: One way to kill foreign invaders is through Phagocytosis and this is when there is a release of enzymes that kill the microbe?
False, phagocytosis is one way to kill foreign invaders but this eats the invaders.
116
True or False: One way to kill foreign invaders is through the releae of enzymes that kill the microbe?
True
117
True or False: One way to kill foreign invaders is through the use of antibodies?
True
118
What are the different ways to kill foreign invaders?
1. Phagocytes 2. Release enzymes that kill the microbe 3. The use of antibodies
119
What is hemostasis?
Hemostasis is the Control of bleeding. Clotting is part of it and platelets are the most important key players.
120
True or False: The 3 mechanisms of hemostasis is Vascular spasm, Protein, and blood clotting?
False, it is vascular spasm | Platelet plug formation, and blood clotting.
121
True or False: The first step for hemostasis is blood clotting?
False, the first step is vascular spasm.
122
True or False: in vascular spasm there is slow constriction of the damaged blood vessel
False, it is a fast constriction of the damaged blood vessel.
123
True or False: in vascular spasm pain receptors stimulate constriction?
True
124
What happens during vascular spasm.
Pain receptors stimulate constriction and in turn results in vasoconstriction, which the diameter of the blood vessel gets smaller.
125
True or False: In platelet plug formation exposed collagen fibers of the vessel promote platelets to become un-attach and float away from the damaged blood vessel?
False, the opposite happens. Exposed collagen fibers of the vessel promote platelets to adhere to it.
126
True or False:In platelet plug formation platelets send out pseudo-pods to make the platelets that are stuck to the vessel wall get unstuck?
False, platelets send out pesudo-pods to stick to the vessel wall. Pesudo-pods constrict to seal the cut.
127
True or False: in platelet plug formation platelets undergo degranulation?
True, this attracts platelets and promote platelet activity.
128
What happens during platelet plug formation?
1. Exposed collagen fibers of the vessel promote platelets to adhere to it. 2. Platelets send out pseudo-pods to stick to the vessel wall. 3. Platelets undergo degranulation.
129
True or False: in the 3 mechanisms of hemostasis, the last step blood clotting, the goal is to convert protein into fibrin?
False, the goal is to convert fibrinogen to fibrin (allowing blood to clot)
130
True or False: There are two pathways for blood clotting?
True, it is extrinsic and intrinsic.
131
True or False: Extrinsic is when it is in the inside of the blood vessel?
False, it is on the outside of the blood vessel. This starts when the tissue factor leak into blood.
132
True or False: Intrinsic is when the inside of the blood vessel starts on the inside?
True, starts when damaged to the endothelial cells or activated platelets.
133
What is the difference between extrinsic and intrinsic pathways in blood clotting?
Extrinsic is on the outside of the blood vessel and intrinsic is in the inside of the blood vessel.
134
True or False: The first step in the blood clotting process is when Thrombin chops up fibrinogen into fibrin.
False, this is the third step. The first step is factor X is activated.
135
True or False: The second step of the blood clotting process is factor XIII cross-links fibrin to make a mesh?
False, this is the 4th step in the blood clotting process. the second step is prothrombin turns into thrombin.
136
True or False: The third step in the blood clotting process is Thrombin chops up fibrinogen into fibrin
True
137
True or False: the 4th step in the blood clotting process is Factor X activated?
False, this is the first step, the 4th step is factor XIII cross-links fibrin to make a mesh.
138
True or False: Calcium plays an important role in the blood clotting process in that it maintains control/ feedback of the system?
True
139
True or False: in the blood clotting process Clot retraction – clot pushes the edges apart so new endothelial cells can repair vessel lining.
False, Clot retraction – clot retracts pulling the edges close together so new endothelial cells can repair vessel lining.
140
What is the blood clotting process?
1. Factor X activated 2. Prothrombin turns into thrombin 3. Thrombin chops up fibrinogen into fibrin 4. Factor XIII cross-links fibrin to make a mesh
141
What is Fibrinolysis
Dissolve small clots and site of damage clots after damage is repaired with use of plasmin
142
What is an Embolus?
A dislodged thrombus, that is transported elsewhere | Common occurrences – pulmonary embolism or stroke
143
What is a thrombosis?
Clotting in an unbroken vessel – thrombus | Caused by atherosclerosis, trauma, infection
144
What is hemophilia?
``` Genetic deficiency of 1 or more clotting factors Inherited from mother Types: Hemophilia A Hemophilia B ```