The Approach to the Patient with Kidney Disease Flashcards

1
Q

Give examples of symptoms which may suggest an Upper Urinary Tract pathology (affecting kidneys)

A

Severe colicky pain which may radiate to groin or testicle, or haematuria

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2
Q

Lower urinary tract symptoms (affecting bladder and urethra) can be divided into two different pathologies - what are they?

A
  • Obstructive voiding

- Storage related

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3
Q

Give six examples of Obstructive Voiding Lower urinary tract symptoms (affecting bladder and urethra)?

A
  1. Hesitancy
  2. Delay in initiating urination
  3. Weak urinary stream
  4. Straining to void
  5. Incomplete emptying
  6. Terminal dribbling
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4
Q

Give six examples of Storage related Lower urinary tract symptoms (affecting bladder and urethra)?

A
  1. Polyuria
  2. Nocturia
  3. Urgency
  4. Incontinence
  5. Bladder pain
  6. Dysuria
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5
Q

What are the three symptoms which describe urine volume abnormalities?

A

Polyuria (high), oligouria (low), anuria (absent)

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6
Q

Give three differentials for polyuria

A

Early chronic kidney disease
Osmotic diuretic use
Post renal obstruction

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7
Q

Give one cause for oligouria

A

Acute kidney injury

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8
Q

Give two differentials for anuria

A

Severe acute kidney injury

Post renal obstruction

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9
Q

Why might urine appear dark yellow?

A

Urine may be concentrated or have presence of bile pigments

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10
Q

Why may urine appear pink?

A

Haematuria or beeturia

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11
Q

Why may urine appear red?

A

Haematuria

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12
Q

Why may urine appear browny red?

A

Muscle breakdown; rhabdomyolysis

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13
Q

Why may urine appear cloudy?

A

Excess white cells due to infection

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14
Q

Why may urine appear frothy?

A

Proteinuria

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15
Q

Why may urine show presence of debris?

A

Infection
Vesico-colic fistula
Renal papillary necrosis

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16
Q

Why may urine show presence of air?

A

Vesico-colic fistula

17
Q

In Urine testing via a Multistix, what enzyme is detected for presence of Leukocytes?

A

Leukocyte esterase

18
Q

In Urine testing via a Multistix, what is detected for presence of bacteria?

19
Q

In Urine testing via a Multistix, what is detected for suggestion of Haemolysis?

A

Urobillinogen

20
Q

In Urine testing via a Multistix, detection of protein suggests?

A

Glomerular injury

21
Q

In Urine testing via a Multistix, detection of a high pH suggests what two differentials?

A

Bacterial infection

Renal tubular acidosis

22
Q

In Urine testing via a Multistix, detection of blood suggests what two differentials?

A

Uroepithelial damage

Glomerular damage

23
Q

In Urine testing via a Multistix, detection of ketones suggests?

A

Ketoacidosis

24
Q

In Urine testing via a Multistix, detection of bilirubin suggests?

A

Obstructive jaundice

25
In Urine testing via a Multistix, detection of glucose suggests?
Diabetes mellitus
26
In a biochemical profile of urine, creatinine levels can be used as an estimate for?
Glomerular filtration rate (GFR)
27
What imaging technique is most appropriate for kidneys? Why?
Ultrasound: cheap, non-invasive, no radiation, no risk, can be used to assess renal size and anatomical features
28
Sodium / water retention can lead to what symptoms?
Periperal oedema - swellings on feet | Pulmonary oedema - breathlessness
29
What is more common, primary or secondary hypertension?
Primary
30
How might secondary hypertension occur by renal artery stenosis?
Renal artery stenosis means BP in kidneys will be low due to reduced perfusion, causing an increase in renin release which causes renin mediated hypertension an a systemic rise in BP
31
How might glomerular damage manifest in urine?
Proteinuria | Visible / non-visible haematuria
32
Describe why PCKD has a bimodal age distribution
Two genes are involved: APKD1, which presents symptoms in pts aged 30-40 and APKD2, which presents symptoms in pts aged 70
33
What is inheritance pattern for PCKD?
Autosomal dominant
34
What are the disadvantages of dialysis use?
1. Patients have complex medical problems 2. Frequent hospital admissions 3. Depression / psychological issues 4. Heavy burden on time 5. Fluid / diet restriction 6. Employment difficulties 7. Impact of home treatments on home 8. Cost to health provider