Thalassemia Flashcards
1
Q
Definition
A
Genetic disorder that leads to abnormal production of hemoglobin
2
Q
Pathophysiology
A
Mutation of genes that control hemoglobin productiob
3
Q
Types
A
Alpha thalassemia
Beta thalassemia
4
Q
AT
A
Severity depends on how many no. of genes are mutated/missing leading to range of diseases(hemoglobin H) to severe anemia
5
Q
BT
A
It is of two types: Major thalassemia(Cooley’s anemia) which is the most severe, and minor thalassemia which is asymptomatic and causes mild anemia
6
Q
Treatment
A
Blood transfusions
Iron chelation therapy
Bone marrow transplant
