thalassaemia Flashcards
1
Q
features of thalassaemias
A
microcytic anaemia
fatigue
pallor
jaundice
gallstones
splenomegaly
poor growth and development
2
Q
investigations in thalassaemias
A
FBC: microcytic anaemia, raised ferritin (iron overload)
haemoglobin electrophoresis
3
Q
management of alpha thalassaemia
A
monitoring
blood transfusion
splenectomy
bone marrow transplant
4
Q
what is beta thalassaemia minor (thalassaemia trait)
A
have one abnormal and one normal gene
causes mild microcytic anaemia only requires monitoring
5
Q
features of beta thalassaemia major
A
frontal bossing (prominent forehead)
enlarged maxilla
depressed nasal bridge
protruding upper teeth
6
Q
management of beta thalassaemia major
A
regular transfusions
iron chelation
splenectomy
bone marrow transplant
