blood film Flashcards
what is anisocytosis
variation in the size of red blood cells
in what conditions do you see anisocytosis
myelodysplastic syndrome
many types of anaemia (iron deficiency, pernicious, autoimmune)
what are target cells
red blood cells with a central pigmented area surrounded by a pale area, surrounded by a ring of thicker cytoplasm
look like a bull’s eye target
what conditions have target cells
iron deficiency anaemia
post-splenectomy/ hyposplenism
sickle cell/thalassaemia
liver disease
what conditions do you see tear-drop poikilocytes
myelofibrosis
what conditions do you see spherocytes
hereditary spherocytosis
autoimmune haemolytic anaemia
what conditions would you associated with basophilic stippling
lead poisoning
thalassaemia
sideroblastic anaemia
myelodysplasia
what conditions would you associated with howell-jolly bodies
hyposplenism
what conditions would you associate with heinz bodies
G6PD deficiency
alpha thalassaemia
what conditions would you associated with schistocytes (helmet cells)
intravascular haemolysis
mechanical heart valve
disseminated intravascular coagulation
what conditions would you associate with pencil poikilocytes
iron deficiency anaemia
what conditions would you associate with burr cells (echinocytes)
uraemia
pyruvate kinase deficiency