questions

Question 1

causes of microcytic anaemia

Answer 1

TAILS
Thalassaemia
Anaemia of chronic disease
Iron deficiency
Lead poisoning
Sideroblastic anaemia

Question 2

what is anaemia of chronic disease

Answer 2

anaemia that often occurs with CKD due to reduced production of erythropoietin but the kidneys
treatment: erythropoietin

Question 3

causes of normocytic anaemia

Answer 3

3As 2Hs
Acute blood loss
Anaemia of chronic disease
Aplastic anaemia
Haemolytic anaemia
Hypothyroidism

Question 4

what is thrombocytosis

Answer 4

abnormally high platelet count

Question 5

causes of thrombocytosis

Answer 5

reactive
malignancy
essential thrombocytosis
hyposplenism

Question 6

what is essential thrombocytosis

Answer 6

megakaryocyte proliferation results in overproduction of platelets
overlaps with CML, polycythaemia vera, myelofibrosis

Question 7

features of essential thrombocytosis

Answer 7

platelet count
both thrombosis and haemorrhage
burning sensation in the hands
JAK2 mutation

Question 8

management of essential thrombocytosis

Answer 8

hydroxyurea
interferon-alpha
low dose aspirin