Thalamus Flashcards
Epithalamus
PINEAL and HABENULAR
Pineal: endocrine organ, releases melatonin, controlled by sympathetics
Habenular nuclei: Limbic relay nuclei goes into brain stem
-“negative reward” by suppressing mesolimic dopamine reward
Dorsal Thalamus
Primary site of relay for all sensory pathways to cerebral cortex
ALSO site of RELAY for cerebellar and basal ganngliar feedback to cortex
Almost all thalamic nuclei project into cortex
Each nucleus receives reciprocal connections from cortex
Internal Medullary Lamina
Splits thalamus
Intra laminar nuclei
Medial Geniculate
Hearing relay
Tonotopically organized input from inferior colliculus
Types of Thalamic Input
- Input relayed to cortex
2. Modulatory input pathways that effect transmission
Thalamic Modulation
Each nuclei contains many inhibitory interneurons (GABA and peptidergic)
Neuromodulatory neurotransmitter systems terminate in nuclei
Two states of thalamic projection neurons
- Tonic mode
2. Burst/oscillatory mode
Tonic Mode
Neurons respond normally to stimuli (i.e. Depolarization and hyperpolarization)
Burst mode
Tonically hyperpolarized
T CALCIUM CHANNELS open
-> depolarization and burst of potentials
State of intrinsic rhythmicity
BURST neurons can’t communicate specific information
Anterior Thalamus
One nuclei
Medial Thalamus
Medial Dorsal Nucleus
Midline nuclei
Lateral Region
Ventral:
- V. Posterior (Medial and Lateral)
- V. Lateral
- V. Anterior
Lateral:
- Pulvinar
- L. Posterior
- L. Dorsal
Diencephalon
Thalamus, epi thalamus, hypothalamus
Metathalamus
Posterior of Pulvinar
Medial Geniculate Body (auditory relay)
Lateral Geniculate Body (visual relay)
4 types of thalamic nuclei
- Relay
- Association
- Nonspecific
- Reticular Thalamic