Textbook Chapter 11 Picornavirus Flashcards
1
Q
Picornaviruses display wide ranges of what?
A
species and cell susceptibilities for viral infections
2
Q
picornaviruses encode their viral proteins as what?
A
large precursor polyproteins that are subsequently cleaved by viral specific proteinases
3
Q
synthesis of picornavirus proteins occurs via a what?
A
an internal ribosome entry site (IRES) found in the 5’ noncoding regions of viral genomic RNAs
4
Q
Picornaviruses carry out membrane bound RNA replication where?
A
in the cytoplasm of infected cells yielding protein linked progreny RNAs
5
Q
many picornaviruses inhibit cellular macromolecules functions during infection like what?
A
host protein synthesis, RNA synthesis, DNA synthesis, or vesicular trafficking
