Tetracyclines

Question 1

Name the Tetracycline’s

Answer 1

Doxycycline
Minocycline
Tetracyline

Question 2

Tetracycline’s MOA

Answer 2

Inhibit bacterial protein synthesis by reversibly binding to 30S subunit of the ribosome

Question 3

Are Tetracyclines bactericidal or bacteriostatic?

Answer 3

Bacteriostatic

Question 4

Tetracycline’s Adverse Effects (common)

Answer 4

Nausea
Vomiting
Tooth discolouration
Photosensitivity

Question 5

Tetracycline’s Counselling

Answer 5

Take with food to reduce stomach upset

Take with a large glass of water and stay upright for at least 30 minutes

Do not take antacids, iron, calcium or zinc supplements within 2 hours of a tetracycline as they may interfere with its absorption

Avoid sun exposure