Metronidazole and Nitrofurantoin Flashcards

1
Q

Metronidazole MOA

A

Interferes with DNA synthesis

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2
Q

Nitrofurantoin MOA

A

Interferes with DNA, RNA and cell wall synthesis

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2
Q

Is Metronidazole and Nitrofurantoin bactericidal or bacteriostatic?

A

Bactericidal

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2
Q

Metronidazole Adverse Effects (common)

A

Nausea
Vomiting
Diarrhoea
Headache
Dizziness

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2
Q

Metronidazole Counselling

A

Avoid alcohol during and up to 24 hours after treatment

Take tablets with food to reduce stomach upset

Take liquid 1 hou before food for absorption

Avoid driving if you are feeling dizzy or confused

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3
Q

Nitrofurantoin Adverse Effects (Common)

A

Nausea
Vomiting
Diarrhoea
Headache

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4
Q

Nitrofurantoin Counselling

A

Take with food to reduce stomach upset

May cause drowsiness or dizziness - if effected do not drive

May make your urine brown

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