Metronidazole and Nitrofurantoin Flashcards
Metronidazole MOA
Interferes with DNA synthesis
Nitrofurantoin MOA
Interferes with DNA, RNA and cell wall synthesis
Is Metronidazole and Nitrofurantoin bactericidal or bacteriostatic?
Bactericidal
Metronidazole Adverse Effects (common)
Nausea
Vomiting
Diarrhoea
Headache
Dizziness
Metronidazole Counselling
Avoid alcohol during and up to 24 hours after treatment
Take tablets with food to reduce stomach upset
Take liquid 1 hou before food for absorption
Avoid driving if you are feeling dizzy or confused
Nitrofurantoin Adverse Effects (Common)
Nausea
Vomiting
Diarrhoea
Headache
Nitrofurantoin Counselling
Take with food to reduce stomach upset
May cause drowsiness or dizziness - if effected do not drive
May make your urine brown