Tetracicline Flashcards

1
Q

Azione

A

Batteriostatica

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2
Q

Cosa fa

A

Si lega a sububita 30s impedendo attacco trna al complesso mrna ribosoma

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3
Q

Via somm

A

Orale

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4
Q

Va evitata somm con

A

Calcio
Alluminio
Ferro bivalente

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5
Q

Spettro

A

Cocchi, bacilli gram+, gram-
Anaerobi
Rickettsie
Clamidia
Micoplasma
Spirochete
Protozoi, toxoplasma, plasmodio
Helicobacter

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6
Q

Resistenze

A

Inattivazione farmaco con idrolisi
Diminuzione accesso ai ribosomi

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7
Q

Reazioni avverse

A

Gastrointestinali
Discolorazione denti
Fototossicita

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8
Q

Chi

A

Tetraciclina
Metaciclina
Doxiciclina
Minpciclina

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