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Farmacologia > Macrolidi > Flashcards

Macrolidi Flashcards

1
Q

Chi

A

Eritromicina
Claritromicina
Azitromicina

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2
Q

Cosa fanno

A

Si legano a 50s e inibiscono sintesi proteica

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3
Q

Resistenze

A

Eliminazione attiva farmaco tramite pompa
Produzione metilasi che modificano bersaglio di pompa
Idrolisi enzimatica

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4
Q

Spettro

A

Ampio
Alternativo a pen

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5
Q

Via somm

A

Orale

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6
Q

Usi

A

Infezioni banali prime vie respiratorie
Tonsillite
Faringite
Otite
Infezione periodontali

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7
Q

Azione

A

Batteriostatica

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8
Q

Reazioni avverse

A

Febbre, eosinofilia, reazioni Cutanee
Epatiti colestatiche
Distruzione gastro, nausea e vomito
Tossicità a livello cardiaco, allungamento qt
Disturbi udito

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Farmacologia (25 decks)

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