TETRACICLINAS Flashcards

1
Q

Las tetraciclinas se dividen en?

A

-de vida media corta y larga

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2
Q

Cuales son las tetraciclinas de vida media larga?

A

1-DOXICICLINA

2-TIGECICLINA

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3
Q

ESPECTRO DE DOXICICLINA

A

-intracelulares, cualquier bicho raro

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4
Q

ESPECTRO DE TIGECICLINA

A

-enterobacterias, terapias

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5
Q

MA de tetraciclinas

A

-se unen a la subunidad 30s en una posicion que bloquean la union del RNA

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6
Q

EA de tetraciclinas

A
  • NO EN NIÑOS NI EMBARAZADAS (acumulacion en zonas de crecimiento hueso y dientes)
  • sintomas gastrointestinales
  • reaccion de hipersensibilidad cutanea
  • hipertension craneal benigna
  • alteraciones bioquimicas (citopenias)
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7
Q

INTERACCION CON OTROS FARMACOS

A
  • diureticos tiazidicos
  • disminuyen la eficacia de los anticonceptivos orales
  • aumentan el efecto (ACO, digoxina, litio, metrotexato, teofilina)
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8
Q

ESPECTRO ANTIMICROBIANO DE TETRACICLINAS

A

-brucella, bichos raros, leptospira

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