AMINOGLUCOSIDOS Flashcards

1
Q

Cuales son los aminoglucosidos?

A
1-AMIKACINA 
2-GENTAMICINA
3-ESTREPTOMICINA
4-TOBRAMICINA
5-NEOMICINA
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2
Q

QUE CUBRE LA AMIKACINA?

A

-infecciones graves por gram (-)

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3
Q

QUE CUBRE LA GENTAMICINA?

A

-infecciones graves por gram (+)

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4
Q

QUE CUBRE LA ESTREPTOMICINA?

A

-tuberculosis

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5
Q

QUE CUBRE LA TROBAMICINA?

A

-solo inhalada, para fibrosis quistica (se puede dar solo)

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6
Q

QUE CUBRE LA NEOMICINA

A

-topica (se puede dar solo)

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7
Q

MA de aminoglucosidos

A

-se une a subunidades 30S y 50S de ribosoma y bloquean la lectura del ARN mensajero en fase inicial de sintesis proteica

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8
Q

EA de aminoglucosidos

A
  • nefrotoxicidad
  • ototoxicidad
  • NO UTILIZAR MONOTERAPIA
  • bloqueo neuromuscular
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9
Q

INTERACCION CON OTROS FARMACOS

A

-antibioticos que bloquean la sintesis de la pared bacteriana (betalactamicos, glucopeptidos, fosfomicina)

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