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ANTIBIOTICOS INFECTO 1 > RIFAMPICINAS > Flashcards

RIFAMPICINAS Flashcards

1
Q

Cuales son las rifampicinas?

A

1-RIFAMPICINA
2-RIFABUTINA
3-RIFAXIMINA

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2
Q

MA de rifampicinas

A

-efecto bactericida por inhibicion del ARN polimerasa en subunidad beta. via metabolica citocromo p450

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3
Q

EA

A
  • NUNCA USAR SOLOS
  • alteraciones gastrointestinales
  • rifampicina (orina naranja)
  • hepatotoxico
  • hipersensibilidad cutanea
  • insuficiencia renal aguda
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4
Q

INTERACCIONES CON OTROS FARMACOS

A
  • sinergia in vivo con varios antibioticos
  • combinada con anfotericina B puede aumentar su accion antifungica
  • acelera el metabolismo de muchos farmacos
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5
Q

ESPECTRO MICROBIANO

A
  • cocos gram (+), bacilos gram (-) los que causan diarrea, micobacterias (tuberculosis)
  • liesteria, c.difficille, staph aeurus
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6
Q

BIODISPONIBILIDAD

A

-se disminuyen con alimentos

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ANTIBIOTICOS INFECTO 1 (15 decks)

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