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Yr 1 - Endocrinology > Testing for Hormonal Abnormalities > Flashcards

Testing for Hormonal Abnormalities Flashcards

1
Q

What is a static test?

A

Single blood test used to tell the functionality of a gland

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2
Q

What are static tests used to diagnose?

A

Abnormalities of thyroid and sex glands

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3
Q

What is result (on hormones) of primary hyperthyroidism?

A

High T3 and T4, low TSH

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4
Q

What is result of secondary hyperthyroidism?

A

High T3 and T4, high TSH

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5
Q

What is result of primary hypothyroidism?

A

Low T3 and T4, high TSH

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6
Q

What is result of secondary hypothyroidism?

A

Low T3 and T4, low TSH

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7
Q

What is a stimulation test?

A
  1. Stimulate a gland to produce a hormone
  2. Blood test before and blood test 30 minutes after
  3. If none/little is released we can diagnose under-secretion / gland failure
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8
Q

What are stimulation tests used to diagnose?

A

Suspected hormonal under-secretion where a static test is not enough (if range of hormones is too large)

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9
Q

What is the synacthen test used to test for? What does it involve?

A

Tests for adrenal insufficiency by giving ACTH

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10
Q

What does insulin stress test involve?

A
  1. Deliver insulin to patient
  2. Patient decreases blood glucose (hypoglycaemia)
  3. This stresses the body and forces GH secretion in an attempt to increase blood sugar level
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11
Q

What is pros/cons of insulin stress test?

A

More accurate

Less bearable for patients
Can’t use with patients with epilepsy, heart attacks etc

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12
Q

What tests are used to to test for pituitary failure? How do they test for this?

A

Insulin stress test and glucagon stimulation test. Tests for ACTH and GH response

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13
Q

What does glucagon stimulation test involve?

A
  1. Give patients glucagon
  2. Stimulates pituitary gland to produce GH
  3. GH won’t increase if there is problem
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14
Q

What is pros/cons of glucagon test?

A

Milder - causes less stress

Less accurate

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15
Q

What is a suppression test used to test for?

A

For hormonal over-secretion

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16
Q

What does the steroid suppression test involve?

A

Delivery of external steroids to test for endogenous steroid production. The addition of external steroids should switch off internal steroid production

17
Q

What does the glucose suppression test involve?

A

Delivery of glucose to test for GH secretion. Glucose should switch of GH secretion in normal individuals

Yr 1 - Endocrinology (14 decks)

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