Testicular Cancer Flashcards
Orchiopexy
Fixation of testis
Moving undecended into scrotum
Cryptorchidism
Hidden testicle
% born with undescended pre mature infant
30%
% post mature infant
3% full term
One year old % undecended
80% decent by 1st year
Risks of undescended
Reduced fertility
Increase germ cell tumors
Psychological
Torosian
Hernia
Infarction
What energy is used in an ultrasound
High frequency sound waves
What is a hydrocele
Buildup of fluid around testes
Why hydrocele common?
If the tube (inguinal canal) does not close after testes descend fluid from abdomen may drain and get trapped in scrotum
What is an easy test for a hydrocele
Shining a flashlight behind swollen part of scrotum transillumination test
Varicocele
Accumulation of blood in veins of the spermatic cord due to faulty valves
What age has a 15% varicocele
Puberty?
Germ cells
Immature sperm cells spermatogonia
How are germ cell tumors classified
Non seminomas or seminomas
Non seminomas
Fast aggressive spread quickly
Seminomas
Slow growing
Symptoms
Painless mass on testicle
Pain
Swelling
Treatment
Surgery
Chemotherapy
Radiation
Chemotherapy after orcheiectomy if
Enlarged lymph nodes or cancer in blood samples
Radiation effect
High energy x-rays to target specific area to kill cancerous cells
Tumor marker
A molecule (protein, enzyme, hormone, genetic marker) occurring in blood or tissue whose measurement is useful in diagnosis or management
4 ways to use tumor marker
- Cancer screening
- Diagnosis
- Prognosis
- Monitor
Alpha - fetoprotien (AFP)
Made by immature liver cells in fetus
When do AFP levels even
AFP levels should fall to those of adult in first year of life
High blood AFP
Hepatocellular carcinoma, germ cell, tumor cancer or liver
high HCG levels NORMAL
Pregnancy made by cells of placenta
HCG what is important
Size of tumor
Lactate dehydrogenase (LDH)
Produces energy
ALL TISSUES OF BODY
More LDH?
Cell damage
Ct
Computerised tomography
Ct function
X rays at angle to combine
MRI
Magnet not x ray
Orichectomy
Removal of testis
2 types of testies cancer
Seminomas , non seminomas
Germ Cells produce gametes
Eggs / sperm
Stage spread to lungs and brain cells
Stage 3C (like stage 4)
Stage 2
Lymph spread
TNMS
Staging system
T-tumor
N-node
M-metastasis (distant)
S-blood
Confined and not spread
Stage 1
Enlarged lymph nodes
Stage 2
Chemotherapy
Targets rapidly dividing cells
Normal cells are damaged leading to
Fatigue
Hair loss
Loa
N&V
Metallic taste
Loss fertility
How long will frozen sample be stored?
Until diner is 55 years
Partial
Shrunk
Stable
Remains same
Complete
All gone :)
Progression (disease)
Still growing
RPLND
Retroperinetal lymph
Node dissection
Remove lymph nodes