Hepatitis Flashcards

1
Q

Nutrient rich, partially deoxygenated blood flows to the liver through the:

A

Hepatic portal vein

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2
Q

What is a virus

A

A small capsule that encloses proteins

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3
Q

How is viral replication different than other living organisms

A

Virus needs host to reproduce

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4
Q

How does a virus destroy the cell it inhabits?

A

Replicates until the cell bursts

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5
Q

The hepatic virus infects what type of liver cells?

A

Liver (hepatic) cells

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6
Q

jaundice

A

Yellowish skin and sclerae (white of eyes) abnormally high levels of bile pigment bilirubin

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7
Q

Where does bilirubin come from

A

Red blood cells are broken down and hemoglobin is broken down into a protein bilirubin liver processes

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8
Q

Why are individuals with hepatitis virus jaundiced?

A

The virus infects liver cells, damaging them. The liver cannot breakdown bilirubin causing elevated blood levels

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9
Q

Symptoms (male)

A

Fatigue, nausea with vomiting, jaundice, fever, chills, abdominal pain

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10
Q

Symptoms (female)

A

Fatigue, decreased appetite, weight loss, aching In abdominal

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11
Q

Hepatitis

A

Inflammation of the liver

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12
Q

Four functions of liver

A
  1. Manufacturers essential proteins
  2. Acts as storage unit for sugars,vitamins, fats
  3. Small compounds into larger ones (cholesterol)
  4. Purifies blood
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13
Q

What hepatitis causes an acute disease but not a chronic disease?

A

Hepatitis A

(A for acute)

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14
Q

What hepatitis is spread through blood transfusion, sex, and needles?

A

Hepatitis B

(B for blood)

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15
Q

Which Hepatitis is spread through feces via contaminated food and water?

A

Hepatitis A

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16
Q

Approximately 90% of transfusion-associated hepatitis is what type?

A

Hepatitis C

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17
Q

Why is hepatitis A endemic to the region

A

Poor sanitation, food and water might be contaminated. People in this region will be affected

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18
Q

What is a carrier

A

Asymptomatic but has the virus

19
Q

When does hepatitis become infectious

A

When the organism produces sufficient tissue damage through many different mechanisms

20
Q

Which liver enzyme is the most specific for hepatocyte damage?

21
Q

Which lab tests can indicate hepatitis

A

CBC
Urinalysis
Chemistry panel (liver enzymes and bilirubin)

22
Q

Which hepatitis symptom is correctly linked to an elevated bilirubin level?

23
Q

Why is bilirubin elevated?

A

When the liver cells are damaged they don’t breakdown bilirubin

24
Q

Dehydration

A

Loss of water and important salts like potassium (K+) and sodium (Na+)

25
What organs are affected by dehydration?
-Brain -heart -kidney
26
How is dehydration treated?
Treat cause and replace fluids
27
Chemistry panel
elevated liver enzymes, bilirubin Slightly decreased albumin level (liver damage)
28
Long term consequences of chronic hepatitis
Chronic infections could lead to long term scaring of liver , liver cancer, liver failure and death
29
Hep A vs Hep B treatments
-Acute symptoms are both treated -**b** may lead to chronic infection and treated with interferon drug to boost immune system
30
Physician (internal medicine)
Diagnostic problems Manage long term problems Expansive
31
Physician (infectious disease)
Diagnosing and managing infections (Unusual or idiopathic)
32
Med lab tech
Analyzes biological specimens Testing and reporting to physician
33
Nurse
Patient care and education
34
What is the function of bile
Fat/ lipids
35
What is the principle component of bile
Bilirubin
36
Bile canaliculi
Drain bile
37
Hepatic sinusoids
Highly permeable blood capillaries
38
Hepatocytes
Main functional cell of the liver
39
Kupffer cells
Phagocytosis Destroy worn out cells, bacteria
40
Attachment
Binds to cell receptor to enter cell
41
Penetration
Enter cell through endocytosis or fusion of membranes
42
Synthesis
Use material to manufacture new viruses
43
Maturation
Parts are assembled to make new virions
44
Release
New virions depart from host cell