Test 7 Reproductive Female Flashcards
What structures are included as part of the Female Reproductive System?
Ovaries Fallopian Tubes (Uterine Tubes, Oviducts) Uterus Vagina Vulva (Pudendum) -Labia Majora -Labia Minor -Clitoris Mammary Glands (considered both integumentary and reproductive)
What Female Reproductive structure resembles unshelled almonds in size and shape, produce gametes and hormones?
Female Gonads (Ovaries)
What hormones are produced by the female gonads (Ovaries)?
Progesterone
Estrogen
Inhibin
Relaxin
The Ovaries are on each side of the Uterus and held in place by what?
Broad Ligament (Fold of Parietal Peritoneum) Ovarian Ligament (Anchors Ovaries to Uterus) Suspensory Ligament (Attaches Ovaries to Pelvic Wall)
What is the point of entrance/exit for blood vessels and nerves that each Ovary Contains?
Hilum (Hilus)
What tissue covers the Ovaries?
Germinal Epithelium
What is the white capsule of dense irregular connective tissue that is deep to the germinal epithelium called?
Tunica Albuginea
What structure lies deep to the tunica albuginea and consists of ovarian follicles which are surrounded by dense connective tissue layer that contains collagen fibers and fibroblast-like cells called stromal cells?
Ovarian Cortex
What structure lies Deep to the ovarian cortex and consists of more loosely arranged connective tissue which contains blood vessels, lymphatic vessels, and nerves?
Ovarian medulla
Where do the Ovarian Follicles lie and what do they consist of?
Ovarian Cortex
CONSTIST: Oocytes in various stages of development plus follicular cells that surround the follicles
Follicular cells are associated with what stage of follicle and what is the cell arrangement?
Cells are in Single Layer
i.e.: Primordial Follicle
What is another term used to describe Follicular cells when the cells are in multiple layers? At what stage of follicle development is this seen?
-Granulosa Cell
Stage:
-Primary and Secondary Follicles
When the follicle is large, fluid filled, ready to rupture and expels the secondary oocyte (process of ovulation), it is referred to as?
Mature (Graafian) Follicle
The Corpus Luteum (Yellow Body) contains what and produces what?
Contains: Remnants of mature follicle after ovulation
Produces: Progesterone, Estrogens, Relaxin, and Inhibin until it degenerates
What does the Corpus Luteum (Yellow Body) degenerate into?
Corpus Albicans (scar tissue)
When does the process of Oogenesis (formation of gametes in ovaries) begin for females?
Before birth
During fetal development what cells migrate from the yolk sac to the ovaries?
Primordial Germ Cells
What do the Primordial Germ Cells differentiate into once in the ovaries?
Oogonia Stem Cells
What is occurring with the Oogonia Stem Cells in the ovaries during fetal development?
- Oogonia are diploid (2n) stem cells
- Under go Mitosis to produce million of germ cells
Prior to birth most of the Germ Cells degenerate by atresia, how many will develop into primary oocytes?
200,000- 2,000,000
The primary oocytes that remain will under go what?
- Begin Meiosis I
- Become “Arrested” in prophase until puberty
What are the primary oocytes surrounded by during the arrested phase? The entire structure is called what?
Single Layer of follicular Cells
Structure: Primordial Follicle
By puberty how many Primary oocytes typically remain and of those approx. how many will mature and ovulate during a woman’s reproductive lifetime?
- Puberty: 40,000 Primary Oocytes
- Mature and Ovulate: 400 in reproductive lifetime
- The remainder undergo atresia
Every month from puberty to menopause FSH and LH stimulate development of several primordial follicles (typically only one reaches maturity for ovulation), and the primordial follicle turns into a primary follicle which is consists of what?
- Primary Oocyte surrounded by several layers of granulosa cells
- Zona pellucida: Glycoprotein layer between primary oocyte and granulosa cells
- Theca folliculi: stromal cells surrounding basement membrane
As the Primary follicle matures it develops into what and what changes are seen?
Secondary Follicle
- Theca Interna: highly vascularized cells, secrete estrogens
- Theca Externa: Outer layer of stromal cells and collagen fibers
- Granulosa Cells: Secrete follicular fluid in antrum (center of 2ndary follicle)
- Corona Radiata: Inner most layer of granulosa cells attached to zona pellucida
The secondary follicle will become what?
Mature (graafian) follicle
What occurs just before ovulation of the mature follicle?
1) Diploid primary oocyte completes meiosis I
(Produces 2 haploid (n) cells of unequal size)
(Each has 23 chromosomes)
The smaller haploid cell that formed from meiosis I of the primary oocytes called what?
First Polar Body: packet of discarded nuclear material
The larger haploid cell that formed from meiosis I of the primary oocytes is called what and what occurs to it?
Secondary Oocyte
- Receives most of the cytoplasm
- Begins Meiosis II but stops in metaphase
- Released (Ovulation)
What is expelled with the secondary Oocyte into the pelvic cavity during Ovulation?
First Polar Body and Corona Radiata
Normally all is “swept” into fallopian tubes, what occurs if Fertilization does not occur?
All cells degenerate
After Ovulation if Sperm are present and penetrate the secondary oocyte what occurs?
Meiosis II Resumes
-Secondary Oocyte splits into two haploid cells
(Ovum + nuclei of sperm= diploid zygote)
-Second polar body: is smaller and leftovers
How is the oocyte pulled into the Fallopian tubes after ovulation?
- Fimbraie on the end of the fallopian tube produces currents
- Current pulls oocyte from peritoneal cavity into fallopian tube
How is the Oocyte carried through the fallopian tube to the uterus?
Peristaltic movements of tubal layers
Where is the typical location in which sperm encounter the secondary oocyte for fertilization? Where else can this occur?
Ampulla of Fallopian Tube
May occur in peritoneal cavity
The Zygote (haploid ova + haploid sperm =(2n) zygote), moves towards the uterus, how long after ovulation does the zygote arrive in the use for implantation in the uterine wall?
6-7 Days after
What structure of reproduction lies superior to the bladder in an Anteflexion (body projects anteriorly over bladder) position and lies Anterior to the rectum?
Uterus
What is the Anatomy of the Uterus?
- Fundus: Top
- Body: Central portion
- Cervix: Inferior extension into vaginal canal
- Isthmus: Region between body and cervix
- Uterine Cavity: Interior of Body
- Cervical Canal: Interior of Cervix
What are the names of the proximal and distal openings of the cervical canal?
Internal os: Open into uterus
External os: Open into vagina
What are the Three histological layers of the Uterus from External to Internal?
Perimetrium (Serosa)
Myometrium
Endometrium
The Perimetrium (serosa) is part of what?
Visceral Peritoneum
The Perimetrium becomes what laterally, and covers and forms what Anteriorly and Posteriorly?
- Laterally: Becomes Broad Ligament
- Anteriorly: Covers Bladder; Forms Vesicouterine Pouch
- Posteriorly: Covers Rectum; Forms Pouch of Douglas (Rectouterine Pouch)
What does the Myometrium consist of?
Three layers of smooth muscle
What are the layers of the Endometrium?
- Stratum Functionalis Layer: Shed during menstruation
- Stratum Basalis Layer: Permanent, gives rise to new stratum functinoalis
The Broad Ligament is double folds of peritoneum and attaches the uterus to where?
Each side of pelvic cavity
What ligament is peritoneal extensions and life on either side of rectum connecting uterus to sacrum?
Uterosacral Ligament
What ligament is inferior to the base of the broad ligament and extends from pelvic wall to cervix and vagina?
Cardinal (Lateral)Ligament
What fibrous connection tissue between broad ligaments extends from point on uterus just inferior to fallopian tubes to portion of labia majora?
Round Ligaments
The Uterine Arteries that supply blood to the uterus are branches of what artery?
Internal Iliac Artery
What branches from the uterine arteries are arranged in circular fashion in the myometrium?
Arcuate Arteries
Which arteries penetrate deeply into myometrium and what are they a branch of?
Radial Arteries via the Arcuate Arteries
The Radial Arteries branch into what just before they enter the endometrium?
- Straight Arterioles: Supply Stratum basalis
- Spiral Arterioles: Supply Stratum Functionalis
The uterine veins empty into what?
Internal Iliac Veins
What is the most inferior portion of the uterus that extends into the vaginal canal called?
Cervix
What term refers to the portion of the cervix that encompasses external cervix and os, usually 1 in in diameter?
Ectocervix
What is the Endocervix?
Encompasses endocervical canal to internal os
What produces Cervical Mucus?
Secretory Cells of Cervix
What is significant of the Cervical Mucus during times of ovulation?
Less Viscous
More Alkaline
=More friendly to Sperm
What is the tubular, 4 inch long fibromuscular canal, lined w/mucous membrane that extends from exterior of body to cervix?
Vagina
The vagina serves what purposes and is situated between what?
Receptacle for penis
Outlet for menstrual flow
Passageway for birth
Situated between: Bladder and Rectum
What is the fornix?
Recess that surrounds vaginal attachment to cervix
What are the layers of the vagina?
- Adventitia: Anchors vagina to adjacent organs
- Muscularis: Outer circular and inner longitudinal layers of smooth muscle
- Mucosa: Continuous w/that of the uterus