Test 6- Lymphatic And Immune System Flashcards

1
Q

What does the lymphatic system do

A

Filters lymph, maintains fluid balance, and supports immune defense

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2
Q

What is movement of lymph dependent on

A

Movement of lymph dependent on skeletal muscle contractions and veins to prevent backflow

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3
Q

What is plasma called as it moves throughout the body

A

Plasma in blood vessels
Interstitial fluid when outside of capillaries
Lymph when in lymphatic capillaries
Plasma when in subclavian vein

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4
Q

Where does the right lymphatic duct drain lymph from

A

From the upper right side of body (right arm, right side of chest/head/neck)

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5
Q

Where does the thoracic duct drain lymph from

A

From rest of body (left side of body and all lower limbs/parts)

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6
Q

What is edema and what is it caused by

A

Swelling due to trapped fluids in tissues (blockage of the flow of lymph)

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7
Q

Where do fats go from the lacteals and how are they filtered

A

Lacteals from small intestinal villi absorb fats (glycerol and fatty acids), transporting them through lymphatic vessels, passing through lymph nodes that filter toxins, ending up in the bloodstream

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8
Q

Whatre the two primary lymphoid organs and what are primary lymphoid organs

A

Where lymphocytes develop and mature
Red bone marrow and thymus

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9
Q

What does red bone marrow do

A

The stem cells inside produce rbc, wbc, and platelets
B cells/lymphocytes mature here

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10
Q

What does the thymus do

A

Produces hormones called thymosins that cause t cells to mature

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11
Q

When is thymosin active until, why is this significant

A

Only until around puberty, so its better for kids to be exposed to microbes early, maturing as many t cells as they can to get a large library of wbc

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12
Q

What are secondary lymphoid organs and the two organs that are

A

Lymph nodes and spleen
Where lymphocytes/cells respond/activate

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13
Q

What do lymph nodes do, where are they found

A

Located at certain points along lymphatic vessels
Contains lymphocytes and macrophages that filter out pathogens from lipids

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14
Q

Whats immunity

A

The bodys ability to defend against infection

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15
Q

Whats innate immunity

A

Immunity that functions without previous exposure to pathogens

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16
Q

What is apart of innate immunity

A
  1. Physical chemical barriers
  2. Inflammatory response
  3. Macrophages and dendritic cells
  4. Phagocytes and natural killer cells
17
Q

What is caused by the inflammatory response

A

Injury site becomes enflamed (redness, heat, pain, swelling)
Damaged tissue and granular wbc release histamine

18
Q

What does histamine do, where is it found

A

Its a vasodilator, so it dilates/widens blood vessels, increasing blood flow (with wbc) to injury
Found in the vesicles of granular wbc

19
Q

Whats the inactive version of macrophages

A

Monocytes

20
Q

what do macrophages and dendritic cells do and release and what does this cause

A

Engulfs pathogens and release cytokines
Promotes fever (to kill bacteria, slight temp increase speeds enzymes up)
Promotes wbc production
Activates other immune cells (like other macrophages)

21
Q

What do natural killer cells do, are they specific

A

Kill virus infected and tumor cells by cell to cell contact, nonspecific

22
Q

Why does it initiate and whats adaptive immunity? How long does it take to activate

A

Initiates when immune response fails to remove invaders
Specific, slow
5-7 days to activate

23
Q

Whatre the two parts to adaptive immunity

A

Cell mediated immunity
Antibody mediated immunity

24
Q

What does cell mediated immunity involve

A

Involves helper t cells and cytotoxic t cells

25
Q

When do macrophages become antigen presenting cells, who do they present it to

A

Macrophage that has engulfed a pathogen is now presenting an antigen on its membrane protein, now an apc
Th and tc cells recognize invaders presennted by macrophages

26
Q

What do th cells do

A

Releases cytokines that activate b cells

27
Q

What do tc cells do and how

A

Recognizes infected cells by the antigen presented on the apc’s membrane
Tc cells targets and kills infected cells

28
Q

What are activated b cells called, why, what are they activated by

A

Plasma cells, because they produce antibodies in the plasma
Activated by cytokines from th cells

29
Q

What do antibodies do

A

Attach to and mark the invader to be engulfed by phagocytes

30
Q

What memory cells are there, what do they do

A

Memory b and t cells
Retains information about the bodys past battles, making you more equipped for the same fight against the same pathogens again

31
Q

what does the spleen do and contain

A

same as lymph nodes, contains lymphocytes that filter out pathogens
contains lymphoid tissue and lymphocytes