Test 5- Circulatory System Flashcards
Whatre the three main types of blood vessels, order them from thick to thin, which carry blood away and to the heart?
Arteries: thick layer of smooth muscle to carry blood away from the heart
Veins: Thin layer of smooth muscle with valves to carry blood back to the heart and prevent back flow
Capillaries: Very thin walled vessels to exchange nutrients and wastes with blood vessels
What do capillaries join together
Arterioles (small arteries) to venules (small veins)
Whatre precapillary sphincters and arteriovenuses shunts
Precapillary sphincters within capillaries control blood flow to specific areas
Arteriovenus shunts (also known as as astamoses), are direct connections between the arterioles, can bypass capillary beds to bring blood to an area more needed (running directs some blood away from the digestive system)
What is blood made of
Plasma and formed elements (rbc, wbc, platelets)
What are four plasma proteins, what do they do
Albumin: transports bilirubin from the spleen to the liver
Lipoproteins transport cholesterol
Prothrombin and fibrinogen aids in blood clotting
Where are antibodies produced, whats the scientific name for them, what do they do
Antibodies produced by B lymphocytes (cells), helps fight infection
Immunoglobulins
Whats the scientific name for rbc, what do they contain and not contain
Does not contain a nucleus
Contains hemoglobin to transport oxygen and co2
Where are platelets, rbc, and wbc produced
Red bone marrow
Do rbcs live for a long time? Where do they get dismantled? Whats produced when theyre dismantled and whats reused
They live for around 120 days (not a long time)
They get dismantled in the liver and spleen when worn out
Iron reused to make more rbcs
Heme portion of hemoglobin produces biliverdin, beocming bilirubin
How is bilirubin excreted
Excreted as bile pigments in bile
Whats the stimulus, target, source, and effect of EPO? Whats the full name of EPO?
Erythropoietin
Source: kidneys
Stimulus: kidneys detect low levels of oxygen in the blood
Target: Femur’s red bone marrow
Effect: increases red blood cell production (negative feedback)
What regulates the acid base balance of the blood? How?
Kidneys (and the respiratory system) regulate
ExcretesH+ ions and reabsorbs HCO3- (bicarbonate) ions
When too acidic: hydrogen ions combine with bicarbonate ions to make carbonic acid (H2CO3)
Whats the ph of urine
6 or lower
Whatre the two types of wbcs, whats the scientific name of wbcs, whats the difference between the two types, give examples of the types
Leukocytes
Granular: contains enzymes and proteins that defend against the body by engulfing and digesting antigens with their many vesicles (ex. Neutrophils, eosinophils, basophils)
Agranular: spherical, kidney shaped nucleus, produces antibodies (ex. Monocytes and lymphocytes)
Whats the scientific name for platelets, where do they come from, are they a cell?
Thrombocytes
Comes from large cells produced by the red bone marrow called megakaryocytes, which fragment into platelets
Not cells
What is the role of platelets
Aids in blood clotting
How do platelets help with blood clotting
Releases a clotting factor called prothrombin activator, which helps activate prothrombin
What does prothrombin combine with, what does it become?
Prothrombin combines with calcium ion to become thrombin (active enzyme)
What does thrombin do
Helps fibrinogen combine with calcium ion to form fibrin
Of fibrin and thrombin, which is an enzyme?
Thrombin
What does fibrin do
Forms a mesh made of fibers that traps rbcs, creating a clot to stop/plug the bleeding
What breaks down fibrin
Once tissues start to heal, the enzyme plasmin breaks down the fibrin
Is blood hypotonic or hypertonic to tissue fluid typically
Hypertonic
Why do arteries have higher blood pressure than veins
Because heart directly pumps blood out, while blood returns to the heart via skeletal muscle contractions
Describe what occurs at the arteriole end of capillaries and why this occurs
Because blood pressure is more than osmotic pressure, water, oxygen, and nutrients leave the capillary, by diffusing into the cells
Describe what occurs at the venous/venule end of the capillaries and why this occurs
Because osmotic pressure is more than blood pressure, water and wastes from the tissue body cells re enter the capillary by diffusion