Test #4: Cardiovascular System Flashcards
How many characteristics of blood?
4 characteristics
What are the 4 characteristics of blood?
- Type of tissue; 2. Temperature; 3. Volume; and 4. Weight
What type of tissue is blood?
Blood is a type of Connective Tissue because it has ground substance and extracellular matrix (plasma).
What is the temperature of blood?
Blood is 100.4 °F
What is blood slightly higher than body temperature?
Blood is slightly higher than body temperature due to the metabolic activity of white blood cells.
What is the volume of blood?
Males have 5-6 liters and females have 4-5 liters
What percent of body weight does blood make up?
Blood makes up 8% of body weight.
How many functions of blood?
3 functions
What are the 3 functions of blood?
- Distribution; 2. Regulation; and 3. Protection
Blood: Distribution
Blood transports oxygen (O2), carbon dioxide (CO2), hormones, electrolytes, nutrients, waste, antibodies, vitamins, minerals, proteins, etc.
Blood: Regulation
Blood regulates temperature and pH.
How does blood regulate temperature?
Through vasoconstriction and vasodilation of blood vessels, blood can be rerouted to various regions of the body.
How does blood regulate pH?
pH of blood needs to be 7.35-7.45; buffers (CO2 + proteins) help to regulate pH.
Blood: Protection
White blood cells help to destroy foreign matter (lymphocytes) and clotting proteins help to clot blood at injury sites.
How many main components of blood?
2 main components
What are the 2 main components of blood?
- Plasma; and 2. Formed elements
Blood: Plasma
Plasma makes up 55% of whole blood and is a light, clear, straw-colored fluid containing nutrients, O2, CO2, waste, hormones, etc.
Blood: Formed Elements
Formed elements make up 45% of whole blood and is heavier than plasma.
How many formed elements in blood?
3 formed elements
What are the 3 formed elements in blood?
- Red Blood Cells; 2. White Blood Cells; and 3. Platelets
What are the scientific names for the 3 formed elements?
- Erythrocytes; 2. Leukocytes; and 3. Thrombocytes
Where are the 3 formed elements created?
Formed elements are born in red bone marrow.
What type of cells are the 3 formed elements?
- Red Blood Cells (Erythrocytes) are not true cells (they lack organelles to make space to carry hemoglobin)
- White Blood Cells (Leukocytes) are true cells (they have a full complement of organelles)
- Platelets (Thrombocytes) are not true cells (they are cell fragments)
How long do the 3 formed elements live?
- RBCs live for 3-4 months
- WBCs live for hours to a lifetime
- Platelets live for 5-9 days
What is the “graveyard” for red blood cells (erythrocytes)?
The spleen is the “graveyard” for RBCs (erythrocytes); they are broken down and reused by the body.
What is hemoglobin, what is it made up of, and what is its purpose?
Hemoglobin is a molecule made up of iron, red pigment and protein and oxygen binds to it.
What is the shape of red blood cells (erythrocytes) and platelets (thrombocytes) and why are they shaped that way?
RBCs are biconcave (to bend and fold as they travel through narrow passageways) and platelets have sharp edges (for initiating the blood clotting process).
What is the visible sign of white blood cell (leukocyte) activity?
Pus
What is unique about white blood cells (leukocytes)?
Leukocytes (WBCs) can leave the circulatory system and eat up foreign matter via phagocytosis.
What percentage of each make up formed elements?
- RBCs 99%
2. WBCs <1%
What is hemostasis?
The process of stopping blood loss at the site of a blood vessel tear.
How many steps in hemostasis?
3 steps
What are the 3 steps in hemostasis?
- Vascular spasm; 2. Platelet plug formation; and 3. Coagulation/blood clotting
Hemostasis: Vascular Spasm
Blood vessel spasms and constricts to slow the flow of blood through the area.
Hemostasis: Platelet Plug Formation
Platelets get caught on the exposed collagen fibers at the injury site forming a “plug” to slow blood loss.
Hemostasis: Coagulation/Blood Clotting
RBCs and clotting proteins get caught on the platelet plug forming a mesh or clot over the injury.
What is the heart?
A hollow, muscular organ that brings blood to every cell in the body.
Heart: Size
About the size of a fist, weighing less than a pound.
Heart: Location
a. Sits within the mediastinum (medial cavity of thorax between the lungs).
b. Extends from level of 2nd rib to 5th intercostal space where it rests on the superior surface of the diaphragm.
c. 2/3 of its mass lies to the left side of mid-sternal line.
Heart: Pericardium
The serous membrane which surrounds, protects and anchors the heart.
Pericardium: Fibrous Pericardium
Outer layer of fibrous connective tissue. It anchors and protects the heart.
Pericardium: Serous Pericardium
Deep to the fibrous pericardium, the serous pericardium is a double layer with a space in between called the Pericardial Fluid Space which contains a clear, viscous fluid called serous fluid. The outer layer is the Parietal Layer and the inner layer is the Visceral Layer.
Heart Wall: Epicardium
Outer layer of the heart wall, made up of connective tissue. Deep to the pericardium, the epicardium is the same as the visceral layer of the serous pericardium.
Heart Wall: Myocardium
Middle layer of the heart wall, made up of cardiac muscle. Deep to the epicardium, the myocardium is the thickest layer.
Heart Wall: Endocardium
Innermost layer of the heart wall, made up of epithelial tissue that is smooth and friction free. Deep to the myocardium, the endocardium lines the chambers, covers valves and is continuous with the inner lining of blood vessels.
How many chambers of the heart?
4 chambers
What are the 4 chambers?
1-2. Right and Left Artria; and 3-4. Right and Left Ventricles
Chambers: Atria
Receives blood.
Chambers: Ventricles
Expels blood.
Chambers: Right Atrium
Receives deoxygenated blood from the body.
Chambers: Right Ventricle
Receives deoxygenated blood from the right atrium and expels it to the lungs.
Chambers: Left Atrium
Receives oxygenated blood from the lungs.
Chambers: Left Ventricle
Receives oxygenated blood from the left atrium and expels it to the body.
How many sets of valves of the heart?
4 sets of valves
What are the 4 sets of valves of the heart?
1-2. Atrioventricular Valves (Tricuspid and Bicuspid [Mitral])
3-4. Semilunar Valves (Pulmonary and Aortic)
Valves
Prevents back-flow of blood.
Atrioventricular Valves: Tricuspid
Lies between the right atrium and ventricle.
Atrioventricular Valves: Bicuspid (Mitral)
Lies between the left atrium and ventricle.
Semilunar Valves: Pulmonary
Lies between the right ventricle and pulmonary trunk.
Semilunar Valves: Aortic
Lies between the left ventricle and aorta.
How many major vessels of the heart?
6 major vessels
What are the 6 major vessels?
1-2. Superior and Inferior Vena Cava; 3. Pulmonary Trunk; 4. Pulmonary Arteries; 5. Pulmonary Veins; and 6. Aorta
Major Vessels: Superior and Inferior Vena Cava
Receives deoxygenated blood from the body (SVC from all areas above the diaphragm; IVC from all areas below the diaphragm) and drain into the right atrium.
Major Vessels: Pulmonary Trunk
Receives deoxygenated blood from the right ventricle and splits into the right and left pulmonary arteries.
Major Vessels: Pulmonary Arteries
Receives deoxygenated blood from the pulmonary trunk and sends it to the lungs.
Major Vessels: Pulmonary Veins
Receives oxygenated blood from the lungs and sends it to the left atrium.
Major Vessels: Aorta
The major vessel leaving the heart. It is the largest artery in the body. Receives oxygenated blood from the left ventricle and sends it to the body.
Heart: Interventricular Septum
The wall between the left and right ventricles. It is a thick region of myocardium and is the pathway for electrical energy (Action Potential) traveling down to the ventricles.
How many circulatory pathways?
3 circulatory pathways
What are the 3 circulatory pathways?
- Coronary; 2. Pulmonary; and 3. Systemic
Circulatory Pathway: Coronary
Blood circulatory pathway to the heart itself. It is the shortest of 3 pathways. From the base of the aorta to the heart, then back to the same place the superior and inferior vena cava deposit blood.
Circulatory Pathway: Pulmonary
Circulatory pathway from the heart to the lungs, then back to the heart.
Circulatory Pathway: Systemic
Circulatory pathway that brings oxygenated blood to all cells of the body, then returns deoxygenated blood to the heart.
How many steps of the flow of blood through the heart?
10 steps
What are the 10 steps of the flow of blood through the heart (long)?
- Deoxygenated blood returns (via the superior vena cava and inferior vena cava) from the body and enters the right atrium.
- It then passes through the tricuspid valve and enters the right ventricle.
- Passing through the pulmonary semilunar valve, it enters the pulmonary trunk to the pulmonary arteries.
- It travels through the pulmonary arteries to the lungs.
- In the lungs, the blood gives up carbon dioxide and picks up oxygen.
- The pulmonary veins carry oxygenated blood back to the left atrium.
- Passing through the bicuspid valve to the left ventricle.
- Leaving the left ventricle through the aortic semilunar valve.
- Oxygenated blood enters the aorta where it is sent back out to the body.
- Elastic arteries > muscular arteries > capillaries (gaseous exchange occurs) > venules > veins > superior vena cava and inferior vena cava.
What are the 10 steps of the flow of blood through the heart (short)?
- De-O2 blood (via S.V.C. and I.V.C.) from body > RT atrium.
- Through tricuspid valve > RT ventricle.
- Through pulm. semilunar valve > pulm. trunk > pulm. arteries.
- Through pulm. arteries > lungs.
- In the lungs, blood gives up CO2 & picks up O2.
- Pulm. veins carry O2 blood > LT atrium.
- Through the bicuspid valve > LT ventricle.
- LT ventricle through aortic semilunar valve.
- O2 blood enters aorta to body.
- Elastic arteries > muscular arteries > capillaries (gaseous exchange occurs) > venules > veins > S.V.C. and I.V.C.
Pathology: Myocardial Infarction
“Heart attack” occurs when arteries are blocked 75% or more shutting off blood supply to the heart.
Pathology: Angina Pectoralis
“Choked chest” is pain that is felt in the chest due to a decrease of blood flow to the coronary circulatory system.
Pathology: Incompetent Valve
A valve that allows back-flow of blood due to improper function; causes a “heart murmur”
What is the Intrinsic Conduction System?
The heart’s ability to beat on its own.
How many unique elements of cardiac muscle cells?
2 unique elements
What are the 2 unique elements of cardiac muscle cells?
- Auto-rhythmic cells; and 2. Gap junctions
Cardiac Muscle Cells: Auto-rhythmic Cells
“Excitable cells”
Some cardiac muscle cells are able to depolarize without the need of an action potential/nerve stimulus.
Cardiac Muscle Cells: Gap junctions
Open doorways for action potential to travel to adjacent cardiac muscle cells so they can all contract together.
How many parts to the Intrinsic Conduction System?
5 parts
What are the 5 parts to the Intrinsic Conduction System (ICS)?
- Sinoatrial (SA) node; 2. Atrioventricular (AV) node; 3. Atrioventricular (AV) bundle; 4. Bundle branches; and 5. Purkinje fibers
ICS: Sinoatrial (SA) node
“Pacemaker”
It’s a collection of auto-rhythmic cells located in the upper, right atrium. Generates an action potential at 100 beats per minute (bpm). Slowed to 75 bpm by the parasympathetic nervous system. Controlled by the vagus nerve (cranial nerve #10).
ICS: Atrioventricular (AV) node
Another collection of auto-rhythmic cells located in the lower, right atrium. Generates an AP at 50 bpm.
- Causes a 1/10th second delay of the action potential.
ICS: Atrioventricular (AV) bundle
Auto-rhythmic cells located in the interventricular septum carry the AP down to the ventricles.
Known as “bundle of His”
ICS: Bundle branches
Right and left bundle branches. Auto-rhythmic cells which carry the AP to the ventricles.
ICS: Purkinje fibers
Carry the AP deep into the myocardium of the ventricles.
Vocabulary: Tachycardia
Abnormally fast heart rate @ >100 bpm
Vocabulary: Bradycardia
Abnormally slow heart rate @ <60 bpm
Cardiac Cycle: Systole
Contraction phase of a heart beat
Cardiac Cycle: Diastole
Relaxation phase of a heart beat
How many events associated with one complete heart beat?
3 events
Cardiac Cycle: What 3 events are associated with one complete heart beat, and how long?
- Atrial systole = .1 seconds
- Ventricular systole = .3 seconds
- Total diastole = .4 seconds
One complete heart beat = .8 seconds
What is auscultation?
The diagnostic listening to the sounds of internal organs.
In the case of the heart we listen for the sound of valve closure.
How many characteristic sounds of the heart?
3 sounds
What are the 3 characteristic sounds of the heart?
- Lubb; 2. Dupp; and 3. Pause
Heart Sounds: Lubb
Atrioventricular (AV) valves closing
Heart Sounds: Dupp
Semilunar valves closing
Heart Sounds: Pause
Diastole
“at rest”
What is the formula for cardiac output?
stroke volume * beats per minute
The amount of blood expelled by the ventricles per minute.
Cardiac Volume: Stroke volume
The amount of blood expelled by the ventricles per contraction.
How much blood does the average healthy adult heart contain?
70 ml (~ 2 oz)
What is the cardiac output for the average healthy adult?
Cardiac Output = stroke volume * beats per minute
C.O. = 75 ml blood * 75 bpm = 5,250 ml (5.25 l) blood/min
What 2 things can help regulate stroke volume?
Exercise and massage
Starling’s law of the heart
States that cardiac output and veinous return are directly proportional.
If venous return increases, then cardiac output increases.
If venous return decreases, then cardiac output decreases.
How many things can regulate heart rate?
3 things
What 3 things can regulate heart rate?
- Autonomic Nervous System; 2. Chemicals; and 3. Physical factors
Heart Rate: Autonomic Nervous System
“Fight or flight”: Sympathetic nervous system increases heart rate
“Rest and digest” or “Feed and breed”: Parasympathetic nervous system decreases heart rate
Heart Rate: Chemical
The hormones epinephrine (adrenaline) and thyroxine increases heart rate.
How many physical factors can affect heart rate?
3 factors
What are the 3 physical factors that can affect heart rate?
- Age; 2. Gender; and 3. Exercise
Heart Rate: Physical factors
- Age: Fetal heart rate = 140-160 bpm; declines as we get older.
- Gender: Male heart rate = 64-72 bpm; female 72-80 bpm
- Exercise: increases heart rate
How many structures of blood vessel walls?
5 structures
What are the 5 structures of blood vessel walls?
- Tunica intima; 2. Tunica media; 3. Tunica extrema; 4. Lumen; and 5. Valves
Blood Vessels: Tunica intima
Innermost lining of a blood vessel made up of epithelial tissue.
Blood Vessels: Tunica media
Smooth muscle layer responsible for vasoconstriction and vasodilation.
Blood Vessels: Tunica externa
The outermost layer of connective tissue which anchors blood vessels. It also provides a pathway for blood vessels, nerves and lymphatics.
Blood Vessels: Lumen
The central space where blood flows.
Blood Vessels: Valves
Some vessels (veins) have valves which prevent back-flow of blood.
How many main types of blood vessels?
3 main types
What are the 3 main types of blood vessels?
- Arteries; 2. Veins; and 3. Capillaries
Which direction do the blood vessels travel?
- Arteries travel away from the heart
2. Veins travel toward the heart
What type of blood is carried in the blood vessels?
- Arteries carry oxygenated blood.
- Veins carry deoxygenated blood.
- Except pulmonary arteries and veins.
What is the blood pressure in the blood vessels?
- Arteries have higher blood pressure.
2. Veins have lower blood pressure.
How does the shape of the blood vessels affect blood pressure?
- Arteries narrow as they travel away from the heart, maintaining blood pressure
- Veins act as blood reservoirs; 65% of blood is in the venous system.
Blood Vessel differences: Tunica externa connective tissue
- Thinner for arteries
2. Thicker for veins
Blood Vessel differences: Tunica media (smooth muscle tissue)
- Thicker for arteries
2. Thinner for veins
Blood Vessel differences: Lumen
- Gets smaller for arteries
2. Bigger for veins
Where are blood vessels located?
- Arteries are deep with some local surfacing
2. Veins are superficial and deep
Do blood vessels have valves?
- Arteries do not
2. Some veins do
How many subtypes of arteries?
3 subtypes
What are the 3 subtypes of arteries?
- Elastic; 2. Muscular; and 3. Arterioles
Arteries: Elastic
Major arteries off of heart which need to expand and recoil.
Arteries: Muscular
Serve major regions and organs
Arteries: Arterioles
Smallest form leads into capillaries. Re-routes blood as needed.
How many subtypes of veins?
1 subtype
What is the 1 subtype of vein?
- Venules
Veins: Venules
Smallest form leads into veins from merging capillaries.
How many ways aid venous return?
3 ways
What are the 3 ways that aid venous return?
- Skeletal muscle pump; 2. Respiratory pump; and 3. Swedish massage
Venous Return: Skeletal muscle pump
Skeletal muscle squeezes veins which helps return blood to the heart (e.g. soleus)
Venous Return: Respiratory pump
Contraction of the diaphragm increases abdominal pressure which forces blood in veins back toward the heart.
Venous Return: Swedish massage
Theoretically, the centripetal stroke of effleurage aids in blood flow toward the heart.
Vocab: Thrombus
A blood clot lodged in a blood vessel wall.
e.g. Deep Vein Thrombosis aka DVT
Vocab: Embolus
A traveling blood clot.
Vocab: Varicosity
A dilated vein due to incompetent valves.
What is the most common vein to suffer from vericosity?
Greater Saphenous Vein
Runs up the medial leg (anterior to the medial malleolus) and thigh.
Arterial Pulse
The physical palpation of the expansion/recoil of superficial arteries corresponding to systole/diastole of the ventricles.
What is the most common area to palpate the arterial pulse in Western medicine?
The radial pulse on the anterior wrist.
Blood Pressure
The measurement of the amount of force blood exerts on the insides of the arteries in response to systole/diastole of the ventricles.
What is the formula for blood pressure?
Blood Pressure = systolic pressure/diastolic pressure
e.g. BP = 120/80 mmHg (millimeters of mercury)
How many factors can affect blood pressure?
6 factors
What are the 6 factors that can affect blood pressure?
- Condition of blood vessels; 2. Autonomic Nervous System; 3. Renal factors; 4. Temperature; 5. Hormones; and 6. Diet
Blood Pressure: Condition of blood vessels
Plaques/build up inside arteries will increase the pressure due to less expansion/recoil)
Blood Pressure: ANS
Sympathetic nervous system increases heart rate which increases blood pressure
Parasympathetic nervous system decreases both
Blood Pressure: Renal factors
If blood pressure is too high, then kidneys make more urine to remove water from blood plasma.
If blood pressure is too low, then kidneys retain water/make less urine.
Blood Pressure: Temperature
Heat causes vasodilation which decreases blood pressure.
Cold causes vasoconstriction which increases blood pressure.
Blood Pressure: Hormones
Epinephrine (adrenaline) and thyroxine both increase heart rate and blood pressure.
Blood Pressure: Diet
Eat a healthy diet low in saturated fat, cholesterol, and salt to maintain a healthy blood pressure.
Effects of Swedish Massage
Theoretically increases venous return.
Local effects of deep tissue massage
Research shows that it stimulates mast cells (type of epithelial cell) which produces histamine. It’s a vasodilator that causes capillaries in the area to become more porous and leak. This increases blood flow (hyperemia).
Precautions and Contraindications
If client indicates a cardiovascular issue and is not being medically treated, massage should be avoided until cleared by a physician.