Test 4: Flashcards
Cushing syndrome:
excess production of glucocorticoid hormones, generalized bilateral hyperplasia of adrenal cortex or may be a result of a functioning adrenal or even non adrenal tumor.
Adrenal Carcinoma:
Primary malignancy of the adrenal gland, grows rapidly and are usually large necrotic masses.
Pheochromocytoma:
a tumor that most commonly arrises in the adrenal medulla which produces an excess of vasopressor substances which can cause hypertension.
Neuroblastoma:
a highly malignant tumor of the adrenal medulla, second most common malignancy in children.
Hyperpituitarism/acromegaly:
caused by excessive growth hormone by the pituitary gland, results in acromegaly in adults and gigantism in kids.
Hypopituitarism:
diminished hormone secretion by the pituitary gland, causes profound generalized disturbances in bone growth and maturation, in children it results in dwarfism.
Diabetes insipidus:
the inability of the kidneys to conserve water, results from low antidiuretic hormone or when kidney fails to respond to circulating ADH.
Hyperthyroidism & Graves:
Excessive thyroid hormone production.
Graves’ disease when entire gland is affected
Hypothyroidism:
Diminished thyroid hormone production, can result in structural/functional abnormality
What is the master gland?
Pituitary gland. The pituitary hormone secretions are controlled by the hypothalamus,
Sits in sella turcica and is divided into anterior and posterior portions
Hyperparathyroidism:
Excessive secretion of parathyroid hormone, results in generalized disorder of calcium, phosphate and bone metabolism that causes elevated levels of calcium and phosphate
Diabetes melitis:
Beta cells in islets of Langerhans of pancreas fail to secrete insulin, lack of insulin prevents glucose from entering cells, results in hyperglycemia
Endocrine glands:
Biochemial communication network through which several small glands control a broad range of vital body activities Major endocrine glands Pituitary Adrenal Thyroid Parathyroid
Adrenal Gland:
Lies on top of each kidney
Consist of an outer cortex and inner medulla
Secretes epinephrine (adrenaline) and norepinephrine
“fight or flight” hormones secreted in stress situations
Adrenaline stimulates heart activity, raises blood pressure and increases level of blood glucose
Which gland secretes epinephrine?
adrenal
Kaposi sarcoma:
a tumor caused by infection with human herpesvirus 8