Test 3 Intracranial Flashcards
Acute focal neurologic deficit r/t a vascular disorder
Brain attack, aka stroke, aka CVA
- risk factors for?
- older age
- male gender
- african american
- HTN
- smoking
- high cholesterol
- diabetes
- afib
- polycythemia
- sickle cell disease
- atherosclerosis
risk factors for CVA
types of brain attack
- transient ischemic attack
- ischemic: thrombotic/embolic
- hemorrhagic
-blood clot involved (embolism, or thrombosis) that impedes blood flow
ischemic
hypertension, aneurysm, AV malformations, blood disorders, decreasing clotting factors
hemorrhagic
- obstruction of cerebral vessels
- localized cerebral tissue hypoxia
- oxygen depletion (10 seconds)
- glucose and glycogen depletion (2-4 min)
- intracellular ATP depletion (4-5) minutes
Ischemic pathogenesis
evolving stroke 3 areas
(from inside out) necrotic core–>penumbra–>normal tissue
- occurs in larger vessels
- atherosclerotic plaques, particularly at points of arterial bifurcation
thrombotic stroke
- site of origin
- left heart, carotid arteries, aortic arch
- predisposing conditions
- afib, MI, ventricular aneurysm,rheumatic heart disease
cardiogenic embolic stroke
An area of penumbra without a necrotic core
-symptoms resolve within 24 hours
TIA, or mini stroke
- rupture of a blood vessel
- bleeding into brain
- edema
- compression of brain contents
- spasm of adjacent vessels
Hemorrhagic stroke
- Left-sided paralysis “hemiplegia”
- Left-sided neglect
- spatial-perceptual deficits
- tendency to minimize or deny problems
- impulsive
- short attention span
- impaired concept of time
- impairment of judgement
Clinical manifestations of right brain damage
- Right-sided paralysis “hemiplegia”
- Aphasia: expressive/receptive
- Slow/cautious behavior
- Awareness of deficits: depression & anxiety
Clinical manifestations of left brain damage
thrombotic therapy can be given within…?
can be given within 3 hours of onset
antiplatelet drugs are _______with hemorrhagic CVA
contraindicated with CVA
spontaneous, abnormal, synchronous discharges from the cerebral cortex
-d/t a change in the excitability of a neuron or group of neurons
Seizures, aka convulsions
- etiology
- unprovoked: unknown “epilepsy”
- provoked: hyperthermia (< age 5), metabolic disturbances, drugs, brain lesions, eclampsia in pregnancy
Seizures etiology
- pathogenesis for?
- Alterations in cell membrane permeability, ion distribution
- inhibition of cortical or thalamic neuronal activity
- excess acetylcholine
- decreased gamma-aminobutric acid (GABA)
Seizure pathogenesis
Generalized or Partial?
-simultaneous onset of seizure activity in both hemispheres of the cerebral cortex
generalized seizure classification
Generalized or partial?
-activity begins in a localized area of one hemisphere
partial seizure classification
- kind of seizure?
- unilateral twitching
- unilateral tingling or crawling sensations
- conscious
- Jacksonian epilepsy
- Aura
Simple partial seizures
Jacksonian epilepsy
sequential involvement of body parts
- type of seizure?
- conscious but amnesic
- may be provoked
- repetitive movement
- inappropriate behavior
Complex partial seizure
Type of seizure where there is a brief loss of consciousness, younger age
Generalized, absence seizures
- preceeded by an aura: sensory simple partial seizure
- tonic muscle tension
- clonic muscle tension
- clonic muscle jerking
- incontinence (bowel and bladder)
- postictal period
generalized, tonic-clonic seizure