TEST 3 Flashcards

1
Q

Wilms tumor/nephroblastoma

A

-asymptomatic abdominal mass
-2-5yo
-hematuria
-HTN
-Mets to bone and lung
-if pulm mets pt will require whole lung radiation
-does NOT cross midline

-DX:
-US
-CT scan will differentiate it from a neuroblastoma

-Tx-
-nephrectomy with exploration of the other kidney and peritoneum.
-Tumor MUST NOT rupture when being taken out -> worsens prognosis.
-Chemo in all pts -> Actinomycin and Vincristine -> unless Stage 1 or < 500 g in wt

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2
Q

pyloric stenosis

A

-Males
-first 1-12 wks of life
-Projectile nonbilious vomiting
-olive shaped mass, non-tender
-palpable
-peristaltic waves visible

-DX:
-US
-pyloric thickness > 4mm
-length > 14 mm
-barium- string sign, beak sign
-Labs- Hypochloremic hypokalemic metabolic alkalosis

-Resuscitate with:
-NS boluses until urine production.
-Then D5 NS with 10 meq of KCL.
-Must have saline as infants develop hyponatremia.
-ALWAYS include glucose due to low reserves.

-TX-
-Pyloromotomy

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3
Q

meckels diverticulum

A

-MC congenital GI anomaly- 2%
-M>F 2:1
-<2yo
-2ft proximal to ileocecal valve
-<2inches
-can be 2 types of mucosa lining

-can be asymptomatic
-MC- lower GI bleeding -> currant jelly, hematochezia, tar
-RLQ pain

-DX-
-Lower GI bleed workup

-Tx-
-surgical resection
-complications- obstruction (intussusception, volvulus), perforation, hemorrhage

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4
Q

umbilical hernia

A

-opening from umbilical cord
-linea alba doesnt close
-usually no complications and close by 3yo
-can be reduced (unless incarcerated)
-if not closed by 5 -> surgery
-if incarceration or strangulation -> emergent repair

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5
Q

neuroblastoma

A

-MC solid malignancy in children
-palpable abdominal mass
-younger = better prognosis
-secrete catecholamines
-MAY cross midline
-Secretory diarrhea, racoon eyes (mets), HTN, gait abnormalities.
-Involves adrenals but can occur anywhere along sympathetic chain.
-Tumor wraps around vessels instead of invading them.
-mets is rare -> bone and lung

-DX-
-urine/blood catecholamines
-CT/MRI
-scintigraphy / MIBG

-TX-
-Surgery- resection of kidney and adrenal gland.
-Doxorubicin - unresectable tumors.

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6
Q

reducible vs irreducible hernia

A

REDUCIBLE
-may ache but NOT tender to touch
-bulge increases with standing or increased intra-abdominal pressure
-can be treated surgically but doesnt need to

IRREDUCIBLE
-AKA incarcerated
-vascular supply is NOT compromised
-painful enlargement of previously reducible hernia
-can be painless
-can lead to strangulation
-try to reduce -> emergent surgery

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7
Q

strangulated hernia

A

-vascular supply compromised
-pain -> tenderness
-sometimes bowel obstruction -> N/V
-may appear ill -> fever
-surgical emergency
-pain out of proportion to exam
-pain that persists after reduction of hernia

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8
Q

inguinal hernia

A

-75% of abdominal hernia
-M>F 25x
-surgical repair

-INDIRECT
-congenital or acquired
-due to incomplete closure of deep inguinal ring
-can protrude into scrotum
-MC in males and older men -> more common as you age
-through external and internal ring -> outside hesselbach
-lateral

-DIRECT
-acquired
-where the abdominal wall is thinner
-middle aged and elderly
-through external ring -> within hesselbach
-medial

-FEMORAL
-less common
-MC in women
-acquired
-through femoral ring into femoral canal
-below inguinal ligament/crease and middle thigh
-easy to be incarcerated and strangulated

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9
Q

obturator foramen hernia

A

-extremely rare
-F>M
-protrudes through pelvic cavity through obturator foramen
-no bulge!
-can act like bowel obstruction -> N/V
-Howship-Romberg sign: pain and paresthesia over the inner aspect of the thigh down to knee -> from obturator nerve injury
-inner thigh pain on internal rotation of hip
-paralysis of hip adductors

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10
Q

epigastric, spigelian, incisional, umbilical hernias

A

-EPIGASTRIC
-fatty tissue not intestine
-painless
-unable to be reduced

-SPIGELIAN
-edge of rectus abdominus

-INSICIONAL
-high reoccurrance
-risk- wound infection, smoking, ischemia, tension, obesity

-UMBILICAL
-pregnancy

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11
Q

wound

A

-seroma- formation of fluid collection under skin -> no systemic signs (flap surgery)
-wound infections -> purulent
-wound dehiscence -> opening of incision under skin -> fluid under skin -> systemic sx
-evisceration -> can see bowel

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12
Q

hiatal hernia

A

-10% of pts
-heartburn
-sudden regurgitation
-burping
-pain on swallowing hot fluids
-feeling of food stuck in esophagus
-MC- overwt middle aged women and elderly
-pregnancy
-type 2 GEJ stays below diaphragm

-dx-
-barium swallow
-endoscope
-radiograph

-Tx-
-no tx if no symptoms
-wt loss
-eat small meals frequently
-stop smoking
-antacids
-avoid hot, spicy, gassy drinks
-if GERD, failure of tx, large, complications (stricture, ulceration, bleeds) -> surgery for type 1
-all types except type 1 -> nissen fundoplication or hiatoplasty

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13
Q

nissen fundoplication

A

-for hiatal hernia or GERD
-gastric fundus is wrapped around the back of lower esophagus
-360 degrees
-can cause vagus nerve damage -> decrease emptying of stomach -> pyloroplasty (widen pyloric sphincter)

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14
Q
A

hiatal hernia

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15
Q

GERD

A

-loss of LES function
-can cause barrets, schatzki, adenocarcinoma
-hoarse

-dx-
-if red flags do an EGD
-if chronic GERD and >=3 risks for barrets -> EGD

-tx-
-H2, PPI
-Nissen fundoplication (complete
fundoplication)- make new sphincter from stomach

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16
Q

barrets esophagus

A

-MC complication of GERD
-precancerous- squamous -> columnar
-risks- GERD, male, >50yo, white, smoking, obesity, family hx

-dx-
-EGD- Z line displacement >= 1cm

-tx-
-PPI and surveillance
-if no dysplasia f/u
-if low grade -> resection and f/u bx
-if high grade -> resection and ablate

17
Q

achalasia

A

-mobility disorder -> cant relax lower esophageal sphincter
-nonperistaltic contraction of lower 2/3rds
-dysphagia to solid AND liquid
-regurgitation
-wt loss
-retrosternal pain
-pneumonia from aspiration

-dx-
-EGD and barium swallow
-bird beak
-esophageal manometry

-tx-
-pneumatic dilation of LES
-LES myotomy (heller myotomy)- LES incised longitudinally to re-enable passage of food/liquids
-peroral endoscopic myotomy (PEOM)- myotomy of inner circular muscular layer of LES (not the longitudinal)

-high risk- botox, nitrates, CCB

18
Q

preseptal/periorbital cellulitis

A

-soft tissues anterior to orbital septum -> eyelid
-MCC from scratch, bite
-red eye, swelling, systemic signs (fever, preauricular and submandibular adenopathy)
-EOM nontender, normal IOP, normal visual acuity, normal sensation

-clinical dx
-swab for gram stain and culture

-empiric oral antibiotics
-consider IV for young pts with red flags

19
Q

orbital cellulitis

A

-soft tissues posterior to orbital septum -> orbital fat, extraocular muscles, neurovascular tissues
-medical emergency
-MCC- bacterial sinusitis through ethmoid
-infants -> dacryocystitis
-systemic signs of infections
-swelling, fever, tender EOM, elevated IOP, impaired vision
-proptosis, chemosis, decrease visual acuity, ophthalmoplegia, optic neuropathy
-relative afferent pupillary defect (RAPD) aka marcus gunn ->

-clinical dx -> confirmed on CT orbits and sinuses
-blood cultures

-tx-
-empiric IV antibx -> vanco + ??
-surgery and urgent opth consult

-complications- visual loss (optic nerve), orbital compartment syndrome, systemic or CNS infection (meningitis), cavernous sinus thrombosis (bilateral), subperiosteal abscess

20
Q

foreign body

A

-trauma to conjunctiva
-acute pain
-red, tearing
-visual acuity might be affected

-dx
-visual acuity!!!!!
-fluorescein staining and slit lamp
-evert eyelids

-tx
-local anesthetic
-normal saline flush/sterile cotton tip applicator
-antibiotic ointment
-referral if not healing

21
Q

dacryocystitis

A

-nasolacrimal obstruction -> sac infection
-Acute- S. aureus, B-hemolytic strep
-Chronic- S. epidermidis, candida
-Chronic etiology- mucosal degeneration, ductile stenosis, stagnant tears, bacterial overgrowth

-sx-
-Acute- red, swelling, warm, pain, purulent, excessive tearing, fever
-Chronic- excessive tearing, mucopurulent, no acute inflammation, no fever

-dx
-clinical
-culture of discharge (blood culture if fever)
-none, CT for etiology

-tx
-children- oral augmentin, antibx drops
-adults- keflex/augmentin, topical antibx drops
-warm compress
-I&D for abscess

-Dacryocystorhinostomy (DCR)- surgery for the obstruction -> unblocks tear ducts in adults by creating new passage for tears to drain into the nose
-do after infection clears or to prevent reoccurrence in chronic

22
Q

blepharitis

A

-inflammation of eyelids
-S. aureus (ulcerative) or chronic skin condition (non-ulcerative)

-2 types:
-ANTERIOR- outside: skin, eyelashes, follicles
-staph or seborrheic dermatitis

-POSTERIOR- inner: meibomian gland dysfunction
-anatomical obstruction- acne rosacea or seborrheic

-S. aureus- itching, lacrimation, burning, photophobia
-Seborrheic- red lid margin, dry flakes

-dx- clinical

-tx-
-anterior- baby shampoo, bacitracin or erythromycin

-posterior- expression of meibomian gland on regular basis
-if corneal inflammation -> oral antibx
-artificial tears
-cool compress

23
Q

hordeolum

A

-acute inflammation of sweat/sebaceous glands around eyelash
-external vs internal
-S. aureus
-sudden, painful, red
-pus filled
-can rupture with purulent discharge
-can progress to chalazion

-dx- clinical

-tx-
-warm compress
-if persists -> topical antibx (bacitracin/erythromycin)
-I&D or curettage

24
Q

chalazion

A

-secondary to hordeolum
-risk- blepharitis, acne rosacea
-swelling of sebaceous glands around eyelash
-obstruction of sebaceous gland (zeis or meibomian)
-can be caused by chronic blepharitis
-slow growing
-firm, painless, rubbery nodule
-evert to see better
-heavy eyelid
-can cause visual disturbance if large

-dx- clinical

-tx-
-warm compress
-steroid injection
-surgery
-bx
-persistent or recurrent can be a sign of meibomian gland carcinoma

25
Q

viral conjunctivitis

A

-MCC- adenovirus!, HSV, VZV
-inflamed palpebral and bulbar conjunctiva
-often starts unilateral -> bilateral
-clear, watery
-hyperemia- inc blood flow
-ipsilateral preauricular lymphadenopathy
-lacrimation
-viral infection sx

-dx- clinical, URI

-tx-
-self limited- warm compress
-sulfonamide drops to prevent 2ndary bacterial
-topical vasoconstrictors
-herpes- topical and/or systemic antivirals

26
Q

bacterial conjunctivitis

A

-S. pneumoniae (kids), S. aureus (adults), moraxella
-thick mucopurulent discharge -> yellow/green
-difficulty opening eyes in morning

-dx-
-clinical
-gram stain
-high risk- scraping and culture

-tx-
-self limiting
-topical antibx - polytrim or fluoroquinolones
-complications- corneal ulcer

27
Q

gonococcal/chlamydial conjunctivitis

A

-Neisseria gonorrhoeae
-Serotypes A-C -> trachoma
-Serotypes D-K -> adult inclusion conjunctivitis
-Chlamydial (inclusion) conjunctivitis -> sexually active young adults, usually chronic, ulcers
-Mucopurulent discharge
-Conjunctival injection
-Corneal involvement uveitis possible
-Preauricular lymphadenopathy
-Conjunctival papillae
-Chemosis: membranes that line eyelids and surface of the eye (conjunctiva) are swollen

-Dx:
-difficult -> look for systemic sx of STI
-Eye infection > 3 wks not responding to antibiotics
-Fluorescent antibody stain, enzyme immunoassay tests
-Giemsa stain: Intracytoplasmic inclusion bodies in epithelial cells, polymorphonuclear leukocytes and lymphocytes

-Tx:
-Oral: Tetracycline, Azithromycin!, Amoxicillin and erythromycin.
-Topical: erythromycin, tetracycline or sulfacetamide.
-Gonococcal: ceftriaxone 1g IM, and then 1gm IV 12-24 hours later.

28
Q

pterygium

A

-Conjunctiva begins to grow onto cornea
-Etiology: UV sunlight and dry conditions
-Blurred vision.
-Eye irritation-Itching, burning
-During growth -> appears swollen and red
-sand in eye feeling
-grows laterally from nasal conjunctiva

-Complications:
-Blockage of vision as grows onto cornea
-reoccurrence after surgery

-Tx:
-Eye drops to moisten eyes and decrease inflammation
-if inflamed - NSAIDS or steroids
-Surgical excision -> visual impairment, reduced motility, chronic inflammation
-excision with conjunctival autograft - tissue transplant from other eye

29
Q

eye exam

A

-visual acuity:
-myopia- nearsighted (long globe)- can only see close
-hyperopia- farsighted (short globe)- can only see far

-external exam:
-penlight or during slit lamp
-Orbit Inflammation (cellulitis)
-Trauma (ecchymosis)
-Dermatological abnormalities (herpes zoster ophthalmicus)
-lacrimal Inflammation (dacryocystitis, dacryoadenitis)
-Eyelash Inflammation (blepharitis)
-Swelling of the eyelid margins (blepharitis, chalazion, mass)

-EOM:
-CN palsies
-nystagmus or lid lag: sympathetic overactivity, sclera can be seen above iris as he looks down
-strabismus

30
Q

vision

A

-image focused by cornea and lens onto retina
-light absorbed by photoreceptors in retina (rods and cones)
-Macula: cones only. Detailed vision
-Fovea: cones dense. Best visual acuity
-Choroid: provides nutrition to retina
-Cornea: covers iris, pupil, anterior chamber
-Palpebra: protect globe
-Cathus: where lids meet

31
Q

Terminology

A

-Ptosis: drooping of eyelid.
-Ectropion: lower lid outward.
-Entropion: lower lid inward.
-Proptosis: exophthalmos.
-Visual fields: scotomas
-Direct pupillary response.
-Consensual pupil response
-Miosis: constriction.
-Mydriasis: dilation: sympathetic
-Emmetropia: light focused on retina perfect
-Presbyopia: lens cannot accommodate for near objects. Can’t increase refractive power.

32
Q

pupils

A

-argyll robertson- small irregular pupils -> syphillis -> do not constrict from light but they DO constrict on near object (accomodation)

-aniscoria- unequal pupil

-adies tonic pupil- poor light reaction

-optic neuritis -> marcus gunn pupil -> light in consensual eye -> both constrict -> light in affected eye -> no reaction