Test 2 Practice Questions Deck 4 Flashcards
Why is prazosin better than phenoxybenzamine?
Prazosin is selective for alpha-1 agonists
Where do you see ephedrine/pseudoephedrine used?
Hermal Remedies (Ma Huang)
What is the difference between Phenylpropylamine and Phenoxybenzamine?
Phenylpropylamine treats urinary incontinence
Phenoxybenzamine treats urinary retention
What does Reserpine do?
Calming agent for horses on stall rest
Detomidine and Romifidine are used for
Horses for sedation in standing procedures
What animals use Dexmedetomidine?
Small animals
What animals use Xylazine?
Horses, Large animals
What species is most sensitive to Xylazine?
Ruminants
When would you use Atipamezole?
To antagonize Dexmedetomidine
When would you use Yohimbine?
To antagonize Xylazine
Alpha-2 antagonists are used for
Sedation AND analgesia
T/F:
Acepromazine is a sedative, muscle relaxant, and analgesic
FALSE!!!!
NOT an analgesic!
What is the “IM” version of Benzodiazepams?
Midazolam
What drug may cause hepatic necrosis in cats?
Diazepam and Midazolam
What drug is used to stop a chicken from feather plucking?
Haloperidol
What drug is used to calm pigs in a crowded trailer?
Azaperone
If a dog was showing signs of restlessness and urinary retention, this may be a side effect of which drug, that was originally prescribed to treat hypotension?
Phenylephrine
What drug is used to diagnose Narcolepsy in a horse?
Physostigmine
What drug is used to diagnose Horner’s Syndrome?
Phenylephrine
What drug would I use if I want to reduce fat deposition and increase muscle deposition in my finishing cows?
Ractopamine or Zilpaterol
Which drugs can I use to treat Glaucoma?
Brimonidine and Timolol
If a dog had both organophosphate and carbamate toxicity, what drug is used to counteract the effects?
Atropine
Because Rabbits metabolize atropine too quickly, what is used instead?
Glycopyrrolate
If I wanted to give a retinal exam, what drug would I use?
Tropicamide
(increases IOP, but short lasting)
If I wanted to check an animal to see if it had a lesion on Cranial Nerve III,
what drug would I use?
Pilocarpine
What drug is used to increase GI motility in a horse?
Neostigmine
What is used to treat animals with hyperthermia?
Dantrolene
What drug is given to a dog with intervertebral disk disease?
methocarbamol
What is given to an animal in order to intubate it?
Succinylcholine
What drug is excreted in the bile?
Vercuronium
What drug degenerates in plasma?
Atracurium
What drug is antagonized by suggamedex?
Rocuronium
What drug antagonizes NMBs?
Cholinesterase inhibitors
Which CNS depressants are associated with hyperglycemia?
Xylazine
Acepromazine
What is the best sedative to use in a cat with cardiac disease?
Diazepam
Which drug targets pain transmission in the spinal cord?
Xylazine
Hypotension due to alpha-1 blockade is associated with
Chlorpromazine
Phenothiazines that can be used to treat motion sickness are:
Promethazine
Trimeprazine
Why might Epinephrine cause greater hypotension when used with Acepromazine?
Epinephrine cannot activate A-1 receptors due to A-1 blockade by Acepromazine
But it can cause vasodilation due to B-2 activation
Which drugs cause CNS depression due to GABA receptor agonism?
Etomidate
Thiopental
Diazepam
Which drug has no specific reversal agent?
Acepromazine
Which Alpha-2 agonist is the LEAST alpha-2 specific?
Xylazine
Alpha-2 agonist cardiac effects
Initial vasoconstriction and reflex bradycardia
followed by vasodilation, decreased cardiac contractility, and decreased HR
Which group of CNS depressants can be used as EMETICS?
Alpha-2 agonists
Which drugs are associated with catecholamine induced arrythmias?
Thiopental
Halothane
Propofol