Test 2 (muscle organization) Flashcards
Muscle tissues comprise about __of body mass, with skeletal being about __% and cardiac and smooth being __%
half; 30-40, 10
characteristics of muscle tissue (4)
contractility, excitability, extensibility, elasticity
functions of muscle (9)
focusing eye lens, generating heat, maintaining posture, movement, piloerection, protecting deeper organs, regulating passage of materials through hollow organs, regulating pupil diameter, and stabilizing joints.
characteristics of skeletal muscle tissue (3)
long multinucleated cells, striations, voluntary
characteristics of cardiac muscle tissue (4)
short branched cells, intercalated discs, striations, involuntary
characteristics of smooth muscle tissue (3)
thin tapered cells, no striations, involuntary
myo- mys-
muscle
sarco-
flesh
muscle terminology for muscle fiber
cell
skeletal muscles have __ attachments
two or more
skeletal muscle functional classification (2)
orgin, insertion
skeletal muscle gross anatomy with CT sheaths (3)*
whole muscle, fascicle, muscle fiber
skeletal muscle microscopic anatomy (4)
multinucleate, myofibrils, sarcolemma, sarcoplasm
sarcolemma classification
t tubules
sarcoplasm classification
glycosomes, myoglobin, mitochondria, sarcoplasmic reticulum
sarcoplasmic reticulum classification
terminal cisternae
myofibril structure
repeated protein structures, striations are aligned
light and dark bands across multiple myofibrils
thick myofilament proteins (1)
myosin
myosin classifications (3)
head, hinge, tail
thin myofilament proteins (3)
actin, tropomyosin, troponin
muscle organization
*
four main processes of contraction
excitation, coupling, contraction, relaxation
sliding filament theory during contraction
myosin heads bind to actin, linked heads automatically pivot 45°, pulling thin filaments.
sliding filament theory during relaxation
ends of myosin and actin filaments overlap, tropomyosin covers binding sites on actin.
cross bridging
myosin heads bind to actin
events of neuromuscular junction excitation (5)
1 nervous impulse signal reaches axon terminal. 2 Ca++ channels open and Ca++ enters the terminal. 3 Vesicles release acetylcholine by exocytosis. 4 acetylcholine diffuses across the synaptic cleft and binds to receptors. 5 receptors initiate a signal (action potential).
steps of excitation-contraction coupling (2)
1 Action potential (AP) moves across sarcolemma and connected T tubules. 2 AP opens Ca channels in SR, and Ca diffuses into myofibrils.
steps of contraction (3)
1 Ca binds to troponin. 2 Troponin changes shape, moving tropomyosin. 3 Enters cycle
contraction cycle continues if (2)
calcium and ATP are present
steps of muscle relaxation (8)
1 Neural impulse stops. 2 ACh is decomposed by acetylcholinesterase at motor end plate. 3 Sarcolemma returns to resting state (no AP). 4 Ca is actively pumped back into SR. 5 Decrease in Ca causes Ca to detach from troponin, so troponin moves to resting position. 6 ATP binds to myosin heads and breaks cross bridges. 7 Formation of cross bridges is prevented by tropomyosin blocking binding sites on actin. 8 Sarcomeres lengthen.
steps of rigor mortis at death
1 Ca leaks from SR into myofibrils. 2 Tropomyosin shifts and actin-myosin cross bridges form. 3 Cross bridges cannot be broken because there is no ATP.
motor unit
one neuron and all the muscle
fibers it stimulates; 4+
Individual fibers contract __ or __.
all, nothing
The number of motor units firing causes variation in __.
force production
skeletal muscle fiber types
slow oxidative, fast oxidative, fast glycolyptic
slow oxidative skeletal muscle fiber
Small diameter, contracts slowly, resists fatigue, high oxygen demand, lots of myoglobin, mitochondria, and blood capillaries, darker red color.
fast oxidative skeletal muscle fiber
Intermediate diameter, contract rapidly, somewhat slow to fatigue, somewhat high oxygen demand.
fast oxidative skeletal muscle fiber can __ between types depending on __.
convert; training
fast glycolytic skeletal muscle fiber
Large diameter, contracts very rapidly, fatigue quickly, low oxygen demand, few myoglobin, mitochondria, and blood capillaries, lighter white color.
smooth muscle lacks
t tubules and myofibrils
smooth muscle filaments __ in a net-like pattern, connecting at __.
crisscross; dense bodies
smooth muscle contraction is very __ and has a __ duration, making it resistant to __.
slow; prolonged; fatigue
__ store and release neurotransmitters like axon terminals.
Varicosities
Primary mechanism of smooth muscle excitation
nerve fibers have varicosities that form diffuse junctions
other mechanisms of smooth muscle excitation (3)
self-excitatory, hormones, gap junctions