Test 2 (muscle organization) Flashcards

1
Q

Muscle tissues comprise about __of body mass, with skeletal being about __% and cardiac and smooth being __%

A

half; 30-40, 10

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2
Q

characteristics of muscle tissue (4)

A

contractility, excitability, extensibility, elasticity

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3
Q

functions of muscle (9)

A

focusing eye lens, generating heat, maintaining posture, movement, piloerection, protecting deeper organs, regulating passage of materials through hollow organs, regulating pupil diameter, and stabilizing joints.

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4
Q

characteristics of skeletal muscle tissue (3)

A

long multinucleated cells, striations, voluntary

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5
Q

characteristics of cardiac muscle tissue (4)

A

short branched cells, intercalated discs, striations, involuntary

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6
Q

characteristics of smooth muscle tissue (3)

A

thin tapered cells, no striations, involuntary

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7
Q

myo- mys-

A

muscle

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8
Q

sarco-

A

flesh

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9
Q

muscle terminology for muscle fiber

A

cell

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10
Q

skeletal muscles have __ attachments

A

two or more

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11
Q

skeletal muscle functional classification (2)

A

orgin, insertion

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12
Q

skeletal muscle gross anatomy with CT sheaths (3)*

A

whole muscle, fascicle, muscle fiber

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13
Q

skeletal muscle microscopic anatomy (4)

A

multinucleate, myofibrils, sarcolemma, sarcoplasm

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14
Q

sarcolemma classification

A

t tubules

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15
Q

sarcoplasm classification

A

glycosomes, myoglobin, mitochondria, sarcoplasmic reticulum

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16
Q

sarcoplasmic reticulum classification

A

terminal cisternae

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17
Q

myofibril structure

A

repeated protein structures, striations are aligned
light and dark bands across multiple myofibrils

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18
Q

thick myofilament proteins (1)

A

myosin

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19
Q

myosin classifications (3)

A

head, hinge, tail

20
Q

thin myofilament proteins (3)

A

actin, tropomyosin, troponin

21
Q

muscle organization

22
Q

four main processes of contraction

A

excitation, coupling, contraction, relaxation

23
Q

sliding filament theory during contraction

A

myosin heads bind to actin, linked heads automatically pivot 45°, pulling thin filaments.

24
Q

sliding filament theory during relaxation

A

ends of myosin and actin filaments overlap, tropomyosin covers binding sites on actin.

25
Q

cross bridging

A

myosin heads bind to actin

26
Q

events of neuromuscular junction excitation (5)

A

1 nervous impulse signal reaches axon terminal. 2 Ca++ channels open and Ca++ enters the terminal. 3 Vesicles release acetylcholine by exocytosis. 4 acetylcholine diffuses across the synaptic cleft and binds to receptors. 5 receptors initiate a signal (action potential).

27
Q

steps of excitation-contraction coupling (2)

A

1 Action potential (AP) moves across sarcolemma and connected T tubules. 2 AP opens Ca channels in SR, and Ca diffuses into myofibrils.

28
Q

steps of contraction (3)

A

1 Ca binds to troponin. 2 Troponin changes shape, moving tropomyosin. 3 Enters cycle

29
Q

contraction cycle continues if (2)

A

calcium and ATP are present

30
Q

steps of muscle relaxation (8)

A

1 Neural impulse stops. 2 ACh is decomposed by acetylcholinesterase at motor end plate. 3 Sarcolemma returns to resting state (no AP). 4 Ca is actively pumped back into SR. 5 Decrease in Ca causes Ca to detach from troponin, so troponin moves to resting position. 6 ATP binds to myosin heads and breaks cross bridges. 7 Formation of cross bridges is prevented by tropomyosin blocking binding sites on actin. 8 Sarcomeres lengthen.

31
Q

steps of rigor mortis at death

A

1 Ca leaks from SR into myofibrils. 2 Tropomyosin shifts and actin-myosin cross bridges form. 3 Cross bridges cannot be broken because there is no ATP.

32
Q

motor unit

A

one neuron and all the muscle
fibers it stimulates; 4+

33
Q

Individual fibers contract __ or __.

A

all, nothing

34
Q

The number of motor units firing causes variation in __.

A

force production

35
Q

skeletal muscle fiber types

A

slow oxidative, fast oxidative, fast glycolyptic

36
Q

slow oxidative skeletal muscle fiber

A

Small diameter, contracts slowly, resists fatigue, high oxygen demand, lots of myoglobin, mitochondria, and blood capillaries, darker red color.

37
Q

fast oxidative skeletal muscle fiber

A

Intermediate diameter, contract rapidly, somewhat slow to fatigue, somewhat high oxygen demand.

38
Q

fast oxidative skeletal muscle fiber can __ between types depending on __.

A

convert; training

39
Q

fast glycolytic skeletal muscle fiber

A

Large diameter, contracts very rapidly, fatigue quickly, low oxygen demand, few myoglobin, mitochondria, and blood capillaries, lighter white color.

40
Q

smooth muscle lacks

A

t tubules and myofibrils

41
Q

smooth muscle filaments __ in a net-like pattern, connecting at __.

A

crisscross; dense bodies

42
Q

smooth muscle contraction is very __ and has a __ duration, making it resistant to __.

A

slow; prolonged; fatigue

43
Q

__ store and release neurotransmitters like axon terminals.

A

Varicosities

44
Q

Primary mechanism of smooth muscle excitation

A

nerve fibers have varicosities that form diffuse junctions

45
Q

other mechanisms of smooth muscle excitation (3)

A

self-excitatory, hormones, gap junctions