Test 2 lecture 6 Flashcards
What is Peripheral Arterial Disease (PAD)?
Obstruction arteries of the legs
Peripheral arterial disease result in what? and what does this mean?
- Claudication
2. Pain weakness numbness or cramping in muscle due to decreased blood flow
What is the prevalence of PAD?
approximately 8 to 12 million people in the US
Direct medical cost in 2001 due to the impact of PAD
4.37 billion dollars
What group of people does PAD impact?
older people, men , African Americans , people with diabetes
What are the metabolic and neural effects of PAD
1 impaired energy utilization 2 impaired resynthesis of ATP and CP 3 low concentration of ATP and CP 4 loss of muscle fibers 5 lower metabolic efficiency of muscle 6 mitochondrial damage 7 damage to peripheral nerves
what are the risk factors of PAD?
1 older age 2 smoking 3 diabetes 4 dyslipidemia 5 hypertension 6 high C-reactive protein 7 High homocysteine 8 high fibrinogen 9 high blood viscosity 10 family history for cardiovascular disease
intermittent claudication happens to what percentage of PAD patients? It also progressively occurs during what?
1) 35-40 %
2) shorter activity bouts
What are the common comorbidities associated with PAD?
1 Heart disease
2 stroke or cerebrovascular disease
3 pulmonary disease and
4. diabetes
what diagnostic tests are used to identify pad
blood test for risk factors, ankle-brachial index, exercise test, Doppler ultrasound, reactive hyperemia, CT or MR angiogram
What is the ratio used to find the ankle-brachial index or ABI?
SBP and Ankle / SBP in arm
Post-exercise ABI may help identify what?
severe ischemia
Prognosis for PAD is (worse / great) when intermittent claudication is present.
worse
prognosis is poor /great with critical limb ischemia.
poor
prognosis for PAD is (lower/greater) with low functional capacity.
lower
What are some lifestyle modifications that should take place in the treatment of PAD?
smoking cessation, diet, physical activity