Test 2 Intro to Metabolism Flashcards

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1
Q

Catabolism

A

The breakdown of complex molecules into their smaller components

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2
Q

Anabolism

A

The synthesis of complex molecules from their simpler subunits

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3
Q

True or False: Anabolic pathways are typically endergonic

A

True

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4
Q

Energy

A

1.Capacity to do work
2. Cause change

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5
Q

What are two units of energy?

A

Joules and calories

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6
Q

What are the three kinds of work?

A

Chemical, Transport, and mechanical

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7
Q

Thermodynamics

A

The study of energy change in a system

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8
Q

First law of thermodynamics

A

The law of conservation; states that energy can neither be created nor destroyed, and that it can only be transformed or redistributed

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9
Q

Second law of thermodynamics

A

State that entropy (or disorder) in the universe is always increasing

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10
Q

Exergonic reactions

A

Reactions that release energy and have a negative DG

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11
Q

Endergonic reactions

A

Reactions that consume energy and have a positive DG

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12
Q

Energy coupling

A

Occurs when energy released from an exergonic reaction is used to fuel an endergonic reaction.

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13
Q

High-energy compound

A

1.Compound with excess energy
2. Used to drive reactions.

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14
Q

Oxidation

A

The loss of an electron.

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15
Q

Reduction

A

The gain of an electron

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16
Q

In a redox reaction, the electron donor is _________ and the electron accept is _________

A

oxidized; reduced

17
Q

Cellular respiration is a redox reaction in which glucose is (reduced/oxidized)

A

Oxidized

18
Q

Equilibrium constant for an oxidation-reduction reaction (E0)

A

The measure of a reducing agent’s tendency to lose electrons. (Also called the standard reduction potential.)

19
Q

A compound with a more negative E0 is a better electron ______, while a compound with a more positive E0 is a better electron _________.

A

donor; acceptor

20
Q

What are some examples of electron carriers?

A

FAD+, NAD+, NADP+, cytochromes and coenzyme Q

21
Q

True or false: ATP and ADP are electron carriers

A

False

22
Q

Enzyme

A

A biological catalyst that speeds up the rate of reaction by lowering the activation energy–the energy needed for the reaction to proceed through its high-energy transition state.

23
Q

Holoenzyme

A

The protein component of an enzyme (i.e., the apoenzyme) and the nonprotein component (i.e., the cofactor).

24
Q

Apoenzyme

A

The protein component of an enzyme

25
Q

Cofactor

A

1.The nonprotein component of an enzyme
2.Acts as a coenzyme or as a prosthetic group that is firmly attached to the enzyme.

26
Q

What are three factors that impact enzymatic activity?

A

1.pH
2.Temperature
3.substrate concentration

27
Q

Denaturation

A

Protein’s structure and function altered due to change from optimal temperature or pH levels

28
Q

Competitive inhibitors

A

Molecules that attach to the enzyme’s active site, prevent the substrate from binding.

29
Q

Noncompetitive inhibitors

A

Molecules that attach somewhere other than the enzyme’s active site, changing the enzyme’s shape and preventing the active site from accepting the substrate molecule.

30
Q

Feedback inhibition

A

1.When the end product of a metabolic pathway acts as a noncompetitive inhibitor for an enzyme in the metabolic pathway,
2. Shuts down pathway when enough of the end product is produced.